CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018717
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SEC14-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 SEC14L1 
Gene Synonyms/Alias
 SEC14L 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
150TVEKIAMKQYTSNIKubiquitination[1]
160TSNIKKGKEIIEYYLubiquitination[1]
245KLDADYIKRYLGDLTubiquitination[1]
352RLGQMDTKGLVRALGubiquitination[2]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 175 PRELI/MSF1.
 DOMAIN 319 495 CRAL-TRIO.
 DOMAIN 521 674 GOLD.  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 715 AA 
Protein Sequence
MVQKYQSPVR VYKYPFELIM AAYERRFPTC PLIPMFVGSD TVNEFKSEDG AIHVIERRCK 60
LDVDAPRLLK KIAGVDYVYF VQKNSLNSRE RTLHIEAYNE TFSNRVIINE HCCYTVHPEN 120
EDWTCFEQSA SLDIKSFFGF ESTVEKIAMK QYTSNIKKGK EIIEYYLRQL EEEGITFVPR 180
WSPPSITTSS ETSSSSSKKQ AASMAVVIPE AALKEGLSGD ALSSPSAPEP VVGTPDDKLD 240
ADYIKRYLGD LTPLQESCLI RLRQWLQETH KGKIPKDEHI LRFLRARDFN IDKAREIMCQ 300
SLTWRKQHQV DYILETWTPP QVLQDYYAGG WHHHDKDGRP LYVLRLGQMD TKGLVRALGE 360
EALLRYVLSI NEEGLRRCEE NTKVFGRPIS SWTCLVDLEG LNMRHLWRPG VKALLRIIEV 420
VEANYPETLG RLLILRAPRV FPVLWTLVSP FIDDNTRRKF LIYAGNDYQG PGGLLDYIDK 480
EIIPDFLSGE CMCEVPEGGL VPKSLYRTAE ELENEDLKLW TETIYQSASV FKGAPHEILI 540
QIVDASSVIT WDFDVCKGDI VFNIYHSKRS PQPPKKDSLG AHSITSPGGN NVQLIDKVWQ 600
LGRDYSMVES PLICKEGESV QGSHVTRWPG FYILQWKFHS MPACAASSLP RVDDVLASLQ 660
VSSHKCKVMY YTEVIGSEDF RGSMTSLESS HSGFSQLSAA TTSSSQSHSS SMISRWRFC 719 
Gene Ontology
 GO:0005794; C:Golgi apparatus; TAS:ProtInc.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0016020; C:membrane; TAS:ProtInc.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR001251; CRAL-TRIO_dom.
 IPR011074; CRAL/TRIO_N_dom.
 IPR009038; GOLD.
 IPR006797; PRELI/MSF1. 
Pfam
 PF00650; CRAL_TRIO
 PF03765; CRAL_TRIO_N
 PF04707; PRELI 
SMART
 SM01100; CRAL_TRIO_N
 SM00516; SEC14 
PROSITE
 PS50191; CRAL_TRIO
 PS50866; GOLD
 PS50904; PRELI_MSF1 
PRINTS