CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005210
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial import receptor subunit TOM40 
Protein Synonyms/Alias
 Mitochondrial import site protein ISP42; Translocase of outer membrane 40 kDa subunit 
Gene Name
 TOM40 
Gene Synonyms/Alias
 ISP42; MOM38; YMR203W; YM8325.04 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
147RLNYGWDKKNISKVNacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Channel-forming protein essential for import of protein precursors into mitochondria. 
Sequence Annotation
  
Keyword
 Complete proteome; Ion transport; Membrane; Mitochondrion; Mitochondrion outer membrane; Porin; Protein transport; Reference proteome; Transmembrane; Transmembrane beta strand; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 387 AA 
Protein Sequence
MSAPTPLAEA SQIPTIPALS PLTAKQSKGN FFSSNPISSF VVDTYKQLHS HRQSLELVNP 60
GTVENLNKEV SRDVFLSQYF FTGLRADLNK AFSMNPAFQT SHTFSIGSQA LPKYAFSALF 120
ANDNLFAQGN IDNDLSVSGR LNYGWDKKNI SKVNLQISDG QPTMCQLEQD YQASDFSVNV 180
KTLNPSFSEK GEFTGVAVAS FLQSVTPQLA LGLETLYSRT DGSAPGDAGV SYLTRYVSKK 240
QDWIFSGQLQ ANGALIASLW RKVAQNVEAG IETTLQAGMV PITDPLMGTP IGIQPTVEGS 300
TTIGAKYEYR QSVYRGTLDS NGKVACFLER KVLPTLSVLF CGEIDHFKND TKIGCGLQFE 360
TAGNQELLML QQGLDADGNP LQALPQL 387 
Gene Ontology
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.
 GO:0005742; C:mitochondrial outer membrane translocase complex; IDA:SGD.
 GO:0046930; C:pore complex; IEA:UniProtKB-KW.
 GO:0015288; F:porin activity; IEA:UniProtKB-KW.
 GO:0015266; F:protein channel activity; IDA:SGD.
 GO:0006811; P:ion transport; IEA:UniProtKB-KW.
 GO:0030150; P:protein import into mitochondrial matrix; IMP:SGD. 
Interpro
 IPR023614; Porin_dom.
 IPR027246; Porin_Euk/Tom40.
 IPR005686; Tom40. 
Pfam
 PF01459; Porin_3 
SMART
  
PROSITE
  
PRINTS