CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027257
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sorting nexin 18 
Protein Synonyms/Alias
 Sorting nexin-18 
Gene Name
 Snx18 
Gene Synonyms/Alias
 Snag1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
12ARALYDFKSENPGEIubiquitination[1]
317LYARLAEKFPVISVPubiquitination[1]
342FEEDFISKRRKGLIWubiquitination[1]
457GFKKEYQKVGQSFRGubiquitination[1]
604FFQKVTQKLEEALHKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 615 AA 
Protein Sequence
MALRARALYD FKSENPGEIS LREHEVLSLC SEQDIEGWLE GINSRGDRGL FPASYVQVIR 60
APEPGPPADG GPGAPARYAN VPPGGFEPLP AAPPAAFPPL LQPQASPGSF QPPGAGFPYG 120
GGALQPSPQQ LYGGYQASLG SDDDWDDEWD DSSTVADEPG ALGSGAYPDL DGSSSAGGGA 180
AGRYRLSTRS DLSLGSRGVS APPAHQASGA KSSATVSRNL NRFSTFVKSG GEAFVLGEAS 240
GFVKDGDKLC VVLGPYGPEW QENPYPFQCT IDDPTKQTKF KGMKSYISYK LVPTHTQVPV 300
HRRYKHFDWL YARLAEKFPV ISVPHLPEKQ ATGRFEEDFI SKRRKGLIWW MNHMASHPVL 360
AQCDVFQHFL TCPSSTDEKA WKQGKRKAEK DEMVGANFFL TLSTPPAAAL DLQEVESKID 420
GFKCFTKKMD DSALQLNHTA NEFARKQVTG FKKEYQKVGQ SFRGLSQAFE LDQQAFSVGL 480
NQAIAFTGDA YDAIGELFAE QPRQDLDPVM DLLALYQGHL ANFPDIIHVQ KGALTKVKES 540
RRHVEEGKME VQKADGIQDR CNTISFATLA EIHHFHQIRV RDFKSQMQHF LQQQIIFFQK 600
VTQKLEEALH KYDSV 615 
Gene Ontology
 GO:0030136; C:clathrin-coated vesicle; IEA:Compara.
 GO:0031234; C:extrinsic to internal side of plasma membrane; IEA:Compara.
 GO:0030426; C:growth cone; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0035091; F:phosphatidylinositol binding; IDA:MGI.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0006897; P:endocytosis; IEA:Compara.
 GO:0043547; P:positive regulation of GTPase activity; IEA:Compara. 
Interpro
 IPR001683; Phox.
 IPR011511; SH3_2.
 IPR001452; SH3_domain.
 IPR014536; Snx9.
 IPR019497; Sorting_nexin_WASP-bd-dom. 
Pfam
 PF10456; BAR_3_WASP_bdg
 PF00787; PX
 PF07653; SH3_2 
SMART
 SM00312; PX
 SM00326; SH3 
PROSITE
 PS50195; PX
 PS50002; SH3 
PRINTS