CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039251
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Fmnl2 
Protein Synonyms/Alias
  
Gene Name
 Fmnl2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
316GLDEYLDKLKHTESDubiquitination[1]
886FILHNEGKLKKLQDDacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1034 AA 
Protein Sequence
NAMNLPPDKA RLLRQYDNEK KWELICDQER FQVKNPPHTY IQKLKGYLDP AVTRKKFRRR 60
VQESTQVLRE LEISLRTNHI GWVREFLNEE NKGLDVLVEY LSFAQYAVTF DFESVESTVE 120
STVDKSKPWS RSIEDLHRGN NLPSPVGNSV SRSGRHSALR YNTLPSRRTL KNSRLVSKKD 180
DVHVCIMCLR AIMNYQYGFN MVMSHPHAVN EIALSLNNKN PRTKALVLEL LAAVCLVRGG 240
HEIILSAFDN FKEVCGEKQR FEKLMEHFRN EDNNIDFMVA SMQFINIVVH SVEDMNFRVH 300
LQYEFTKLGL DEYLDKLKHT ESDKLQVQIQ AYLDNVFDVG ALLEDAETKN AALERVEELE 360
ENISHLSEKL QDTENEAMSK IVELEKQLMQ RNKELDVVRE IYKDANTQVH TLRKMVKEKE 420
EAIQRQSTLE KKIHELEKQG TIKIQKKGDG DIAILPVVAS GTLPMGSDLA GGNYVGPVPG 480
AASSGPSVPP PPPLPPSSDT PEAAQNGPAS PPMSPPPPPP PPLPGPAAET VPAPPLPPPP 540
PPSAPPLPGT SSPTVVFNSG LAAVKIKKPI KTKFRMPVFN WVALKPNQIN GTVFNEIDDE 600
RILEDLNVDE FEEIFKTKAQ GPAIDLSSSK QKITQKGSSK VTLLEANRAK NLAITLRKAG 660
KSADEICKAI HVFDLKTLPV DFVECLMRFL PTENEVKVLR LYERERKPLE NLSDEDRFMM 720
QFSKIERLMQ KMTIMAFIGN FTESIQMLTP QLHAIIAASV SIKSSQKLKK ILEIILALGN 780
YMNSSKRGAV YGFKLQSLDL LLDTKSTDRK QTLLHYISNV VKEKYQQVTL FYNELHYVEK 840
AAAVSLENVL LDVKELQRGM DLTKREYTMH DHNTLLKEFI LHNEGKLKKL QDDAKIAQDA 900
FDDVVKYFGE NPKTTPPSVF FPVFVRFVKA YKQAEEENEL RKKQEQALME KLLEQEALME 960
QQDPKSPSHK SKRQQQELIA ELRRRQVKDN RHVYEGKDGA IEDIITALKK NNITKFPNVH 1020
SRILETNPTE EPMR 1034 
Gene Ontology
 GO:0030866; P:cortical actin cytoskeleton organization; IEA:Compara.
 GO:0022604; P:regulation of cell morphogenesis; IEA:Compara. 
Interpro
 IPR003104; Actin-bd_FH2/DRF_autoreg.
 IPR016024; ARM-type_fold.
 IPR010472; Drf_FH3.
 IPR010473; Drf_GTPase-bd.
 IPR015425; FH2_actin-bd.
 IPR014768; GTPase-bd/formin_homology_3. 
Pfam
 PF06367; Drf_FH3
 PF06371; Drf_GBD
 PF02181; FH2 
SMART
 SM00498; FH2 
PROSITE
 PS51444; FH2
 PS51232; GBD_FH3 
PRINTS