UniProt Accession

 Q3TMS1_MOUSE; Q3TMS1 

Genbank Protein ID

 AL669849; AL671971; CAAA01083080; CAAA01137842; CAAA01164104; CR392356; CR762384; CT005230; AK165765 

Genbank Nucleotide ID

 BAE38370.1 

Protein Name

 Dedicator of cytokinesis protein 2 

Protein Synonyms/Alias

  

Gene Name

 Dock2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
150	ILLPVITKELKELLE	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 295 AA 

Protein Sequence

Gene Ontology

 GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0030675; F:Rac GTPase activator activity; IMP:MGI.
 GO:0046633; P:alpha-beta T cell proliferation; IMP:MGI.
 GO:0006935; P:chemotaxis; IMP:MGI.
 GO:0007010; P:cytoskeleton organization; IDA:MGI.
 GO:0001768; P:establishment of T cell polarity; IMP:MGI.
 GO:0001771; P:immunological synapse formation; IMP:MGI.
 GO:0001766; P:membrane raft polarization; IMP:MGI.
 GO:0045060; P:negative thymic T cell selection; IMP:MGI.
 GO:0035022; P:positive regulation of Rac protein signal transduction; IC:MGI.
 GO:0045059; P:positive thymic T cell selection; IMP:MGI.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR026791; DOCK.
 IPR026799; DOCK_A. 

Pfam

  

SMART

  

PROSITE

  

PRINTS