CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042308
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Proteasome subunit beta type 
Protein Synonyms/Alias
  
Gene Name
 LOC100719768 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
77RLNLYELKEGRQIKPacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019
Functional Description
 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Nucleus; Protease; Proteasome; Reference proteome; Threonine protease. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 205 AA 
Protein Sequence
QSIMSYNGGA VMAMKGKNCV AIAADKRFGI QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV 60
QTVAQRLKFR LNLYELKEGR QIKPYTLMSM VANLLYERRF GPYYTEPVIA GLDPKTFQPF 120
ICSLDLIGCP MVTDDFVVSG TCAEQMYGMC ESLWEPNMDP EHLFETISQA MLNAVDRDAV 180
SGMGVIVHVI EKDKITTRTL KARMD 205 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005839; C:proteasome core complex; IEA:InterPro.
 GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
 GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro. 
Interpro
 IPR016050; Proteasome_bsu_CS.
 IPR001353; Proteasome_sua/b.
 IPR023333; Proteasome_suB-type. 
Pfam
 PF00227; Proteasome 
SMART
  
PROSITE
 PS00854; PROTEASOME_B_1
 PS51476; PROTEASOME_B_2 
PRINTS