CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013628
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 766 
Protein Synonyms/Alias
  
Gene Name
 ZNF766 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
157QRIYSGVKTHIFNKHubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 9 80 KRAB.
 ZN_FING 187 209 C2H2-type 1; degenerate.
 ZN_FING 215 237 C2H2-type 2; degenerate.
 ZN_FING 243 265 C2H2-type 3.
 ZN_FING 271 293 C2H2-type 4.
 ZN_FING 299 321 C2H2-type 5.
 ZN_FING 327 349 C2H2-type 6.
 ZN_FING 355 377 C2H2-type 7.
 ZN_FING 383 405 C2H2-type 8.
 ZN_FING 411 433 C2H2-type 9.
 ZN_FING 439 462 C2H2-type 10.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 468 AA 
Protein Sequence
MAQLRRGHLT FRDVAIEFSQ EEWKCLDPVQ KALYRDVMLE NYRNLVSLGI CLPDLSIISM 60
MKQRTEPWTV ENEMKVAKNP DRWEGIKDIN TGRSCAVRSK AGNKPITNQL GLTFQLPLPE 120
LEIFQGEGKI YECNQVQKFI SHSSSVSPLQ RIYSGVKTHI FNKHRNDFVD FPLLSQEQKA 180
HIRRKPYECN EQGKVFRVSS SLPNHQVIHT ADKPNRCHEC GKTVRDKSGL AEHWRIRTGE 240
KPYKCKECGK LFNRIAYLAR HEKVHTGESP YKCNECGKVF SRITYLVRHQ KIHTREKPHK 300
CNKCGKVYSS SSYLAQHWRI HTGEKLYKCN KCGKEFSGHS SLTTHLLIHT GEKPYKCKEC 360
DKAFRHKFSL TVHQRNHNGE KPYKCHECGK VFTQVSHLAR HQKIHTGEKP YKCNECGKVF 420
TQNSHLANHQ RIHTGEKPYK CHVCGKVFRH SSWFVQHQRS VHERVLTN 468 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS