UniProt Accession

 HN1_HUMAN; Q9UK76; B2R6K3; Q53FG7; Q7Z2D2; Q7Z2F0 

Genbank Protein ID

 AF086910; AY322169; AY322170; AF348672; AF348672; AF348672; AF177862; AF266846; AF266847; AK223321; AK312613; CH471099; BC001420; BC039343 

Genbank Nucleotide ID

 AAP97140.1; AAP83838.1; AAP83839.1; AAL83903.1; AAP83962.1; AAP83963.1; AAD53312.1; AAQ14298.1; AAQ14299.1; BAD97041.1; BAG35500.1; EAW89244.1; AAH01420.1; AAH39343.1 

Protein Name

 Hematological and neurological expressed 1 protein 

Protein Synonyms/Alias

 Androgen-regulated protein 2 

Gene Name

 HN1 

Gene Synonyms/Alias

 ARM2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
8	MTTTTTFKGVDPNSR	acetylation	[1]
8	MTTTTTFKGVDPNSR	ubiquitination	[2]
46	EQPVRKNKMASNIFG	ubiquitination	[2, 3]
64	ENQASWAKSAGAKSS	ubiquitination	[2, 3]
69	WAKSAGAKSSGGRED	ubiquitination	[2, 3]
148	RRNPPGGKSSLVLG*	acetylation	[1]

Reference

 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 MOD_RES 2 2 N-acetylthreonine.
 MOD_RES 49 49 Phosphoserine (By similarity).
 MOD_RES 54 54 Phosphothreonine.
 MOD_RES 61 61 Phosphoserine (By similarity).
 MOD_RES 80 80 Phosphoserine.
 MOD_RES 87 87 Phosphoserine.
 MOD_RES 88 88 Phosphoserine.
 MOD_RES 92 92 Phosphoserine (By similarity).
 MOD_RES 131 131 Phosphoserine.
 MOD_RES 148 148 N6-acetyllysine.  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 154 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS