CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009272
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DnaJ homolog subfamily C member 5 
Protein Synonyms/Alias
 Cysteine string protein; CSP 
Gene Name
 Dnajc5 
Gene Synonyms/Alias
 Csp 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
33ATSDDIKKSYRKLALubiquitination[1]
41SYRKLALKYHPDKNPubiquitination[1]
46ALKYHPDKNPDNPEAubiquitination[1]
56DNPEAADKFKEINNAubiquitination[1]
58PEAADKFKEINNAHAubiquitination[1]
72AILTDATKRNIYDKYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). 
Sequence Annotation
 DOMAIN 13 82 J.
 MOD_RES 8 8 Phosphoserine.
 MOD_RES 10 10 Phosphoserine.
 MOD_RES 11 11 Phosphothreonine.
 MOD_RES 12 12 Phosphoserine.
 MOD_RES 15 15 Phosphoserine.
 MOD_RES 17 17 Phosphotyrosine.
 MOD_RES 56 56 N6-acetyllysine (By similarity).  
Keyword
 3D-structure; Acetylation; Cell membrane; Chaperone; Complete proteome; Direct protein sequencing; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MADQRQRSLS TSGESLYHVL GLDKNATSDD IKKSYRKLAL KYHPDKNPDN PEAADKFKEI 60
NNAHAILTDA TKRNIYDKYG SLGLYVAEQF GEENVNTYFV LSSWWAKALF VVCGLLTCCY 120
CCCCLCCCFN CCCGKCKPKA PEGEETEFYV SPEDLEAQLQ SDEREATDTP IVIQPASATE 180
TTQLTADSHP SYHTDGFN 198 
Gene Ontology
 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; ISS:UniProtKB.
 GO:0008021; C:synaptic vesicle; IDA:MGI.
 GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI. 
Interpro
 IPR001623; DnaJ_domain.
 IPR018253; DnaJ_domain_CS. 
Pfam
 PF00226; DnaJ 
SMART
 SM00271; DnaJ 
PROSITE
 PS00636; DNAJ_1
 PS50076; DNAJ_2 
PRINTS
 PR00625; JDOMAIN.