Tag | Content |
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CPLM ID | CPLM-003829 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Fasciclin-1 |
Protein Synonyms/Alias | Fasciclin I; FAS I; FCN |
Gene Name | Fas1 |
Gene Synonyms/Alias | CG6588 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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164 | PNNPNALKFLKNAEE | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Neural cell adhesion molecule. |
Sequence Annotation | DOMAIN 22 144 FAS1 1. DOMAIN 166 310 FAS1 2. DOMAIN 317 463 FAS1 3. DOMAIN 467 616 FAS1 4. LIPID 625 625 GPI-anchor amidated alanine (Potential). CARBOHYD 47 47 N-linked (GlcNAc...) (Potential). CARBOHYD 368 368 N-linked (GlcNAc...) (Potential). CARBOHYD 416 416 N-linked (GlcNAc...) (Potential). CARBOHYD 441 441 N-linked (GlcNAc...). CARBOHYD 493 493 N-linked (GlcNAc...); atypical. CARBOHYD 497 497 N-linked (GlcNAc...). |
Keyword | 3D-structure; Alternative splicing; Cell adhesion; Cell membrane; Complete proteome; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Reference proteome; Repeat; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 652 AA |
Protein Sequence | MLNAAALLLA LLCAANAAAA ADLADKLRDD SELSQFYSLL ESNQIANSTL SLRSCTIFVP 60 TNEAFQRYKS KTAHVLYHIT TEAYTQKRLP NTVSSDMAGN PPLYITKNSN GDIFVNNARI 120 IPSLSVETNS DGKRQIMHII DEVLEPLTVK AGHSDTPNNP NALKFLKNAE EFNVDNIGVR 180 TYRSQVTMAK KESVYDAAGQ HTFLVPVDEG FKLSARSSLV DGKVIDGHVI PNTVIFTAAA 240 QHDDPKASAA FEDLLKVTVS FFKQKNGKMY VKSNTIVGDA KHRVGVVLAE IVKANIPVSN 300 GVVHLIHRPL MIIDTTVTQF LQSFKENAEN GALRKFYEVI MDNGGAVLDD INSLTEVTIL 360 APSNEAWNSS NINNVLRDRN KMRQILNMHI IKDRLNVDKI RQKNANLIAQ VPTVNNNTFL 420 YFNVRGEGSD TVITVEGGGV NATVIQADVA QTNGYVHIID HVLGVPYTTV LGKLESDPMM 480 SDTYKMGKFS HFNDQLNNTQ RRFTYFVPRD KGWQKTELDY PSAHKKLFMA DFSYHSKSIL 540 ERHLAISDKE YTMKDLVKFS QESGSVILPT FRDSLSIRVE EEAGRYVIIW NYKKINVYRP 600 DVECTNGIIH VIDYPLLEEK DVVVAGGSYL PESSICIILA NLIMITVAKF LN 652 |
Gene Ontology | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IDA:FlyBase. GO:0050839; F:cell adhesion molecule binding; IDA:FlyBase. GO:0007411; P:axon guidance; IGI:FlyBase. GO:0016338; P:calcium-independent cell-cell adhesion; IDA:FlyBase. GO:0007156; P:homophilic cell adhesion; IDA:FlyBase. GO:0008038; P:neuron recognition; IDA:FlyBase. |
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