CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004453
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 58 
Protein Synonyms/Alias
 Zfp-58; Regulator of sex-limitation candidate 5; Zinc finger protein Mfg-1 
Gene Name
 Zfp58 
Gene Synonyms/Alias
 Mfg-1; Rslcan5; Zfp817 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
402FYSTLDLKKHQKIHEacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
 May have a role during differentiation processes. 
Sequence Annotation
 DOMAIN 2 73 KRAB.
 ZN_FING 78 100 C2H2-type 1; degenerate.
 ZN_FING 106 128 C2H2-type 2.
 ZN_FING 134 156 C2H2-type 3.
 ZN_FING 162 184 C2H2-type 4.
 ZN_FING 190 212 C2H2-type 5.
 ZN_FING 218 240 C2H2-type 6.
 ZN_FING 246 268 C2H2-type 7.
 ZN_FING 274 296 C2H2-type 8.
 ZN_FING 302 324 C2H2-type 9.
 ZN_FING 330 352 C2H2-type 10.
 ZN_FING 358 380 C2H2-type 11.
 ZN_FING 386 408 C2H2-type 12.
 ZN_FING 410 432 C2H2-type 13.
 ZN_FING 438 460 C2H2-type 14.
 ZN_FING 466 488 C2H2-type 15.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 489 AA 
Protein Sequence
MLSFWDVAID FSPEERECLE PDQWDLYRDV MLENYSHLDF LGLALSKPFL VTFLEQRQGP 60
WDVKRQAAAA VHPGKTVNKC KDFSKAFFCK SLLTQHQRIR TGEKAFKCEE CGKAFNNRSN 120
LSEHKRIHTG EKPYKCEECG KAFRIRSKLS THQRVHTGEK PYKCEECGKA FNSHSNLSEH 180
KRIHTGEKPY KCEECGKAFS TRSTYYRHQK NHTGKKPYKC EECAKEFSYP SLLKVHQRIH 240
SAEKSYKCEE CGKPFYCPLL LKKHQIIHSA EKPYKCAECG KAFHYPSLLK RHQRIHAGKK 300
PCKCKDCDRA FYSSAFLKRH QRIHSEENSY KCGECGKRFC SFPHLQYHQR FHSGEKPYKC 360
EQCGKTFSTL SYLPWHKLRH SGEKSYKCEK CGKMFYSTLD LKKHQKIHEY KCGECHYGFP 420
NYAALTAHQR VHTGEKPHVC EQCGKDFSRI DSLNQHQLVH TGEKPYKCEK CGKCFYRSSS 480
LKRHQGIHS 489 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS