Tag | Content |
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CPLM ID | CPLM-036551 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | BCL6 corepressor/retinoic acid receptor alpha fusion protein |
Protein Synonyms/Alias | |
Gene Name | BCOR-RARA |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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1408 | ARRLIVNKNAGETLL | ubiquitination | [1] | 1587 | FFRRSIQKNMVYTCH | ubiquitination | [1] |
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Reference | [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C. Nat Cell Biol. 2012 Oct;14(10):1089-98. [ PMID: 23000965] |
Functional Description | |
Sequence Annotation | |
Keyword | ANK repeat; DNA-binding; Metal-binding; Nucleus; Receptor; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1931 AA |
Protein Sequence | MLSATPLYGN VHSWMNSERV RMCGASEDRK ILVNDGDASK ARLELREENP LNHNVVDAST 60 AHRIDGLAAL SMDRTGLIRE GLRVPGNIVY SSLCGLGSEK GREAATSTLG GLGFSSERNP 120 EMQFKPNTPE TVEASAVSGK PPNGFSAIYK TPPGIQKSAV ATAEALGLDR PASDKQSPLN 180 INGASYLRLP WVNPYMEGAT PAIYPFLDSP NKYSLNMYKA LLPQQSYSLA QPLYSPVCTN 240 GERFLYLPPP HYVGPHIPSS LASPMRLSTP SASPAIPPLV HCADKSLPWK MGVSPGNPVD 300 SHAYPHIQNS KQPRVPSAKA VTSGLPGDTA LLLPPSPRPS PRVHLPTQPA ADTYSEFHKH 360 YARISTSPSV ALSKPYMTVS SEFPAARLSN GKYPKAPEGG EGAQPVPGHA RKTAVQDRKD 420 GSSPPLLEKQ TVTKDVTDKP LDLSSKVVDV DASKADHMKK MAPTVLVHSR AGSGLVLSGS 480 EIPKETLSPP GNGCAIYRSE IISTAPSSWV VPGPSPNEEN NGKSMSLKNK ALDWAIPQQR 540 SSSCPRMGGT DAVITNVSGS VSSAGRPASA SPAPNANADG TKTSRSSVET TPSVIQHVGQ 600 PPATPAKHSS STSSKGAKAS NPEPSFKANE NGLPPSSIFL SPNEAFRSPP IPYPRSYLPY 660 PAPEGIAVSP LSLHGKGPVY PHPVLLPNGS LFPGHLAPKP GLPYGLPTGR PEFVTYQDAL 720 GLGMVHPMLI PHTPIEITKE EKPERRSRSH ERARYEDPTL RNRFSEILET SSTKLHPDVP 780 TDKNLKPNPN WNQGKTVVKS DKLVYVDLLR EEPDAKTDTN VSKPSFAAES VGQSAEPPKP 840 SVEPALQQHR DFIALREELG RISDFHETYT FKQPVFTVSK DSVLAGTNKE NLGLPVSTPF 900 LEPPLGSDGP AVTFGKTQED PKPFCVGSAP PSVDVTPTYT KDGADEAESN DGKVLKPKPS 960 KLAKRIANSA GYVGDRFKCV TTELYADSSQ LSREQRALQR AMMRFSELEM KEREGGHPAT 1020 KDSEMCKFSP ADWERLKGNQ DKKPKSVTLE EAIAEQNESE RCEYSVGNKH RDPFEAPEDK 1080 DLPVEKYFVE RQPVSEPPAD QVASDMPHSP TLRVDRKRKV SGDSSHTETT AEEVPEDPLL 1140 KAKRRRVSKG LHPKKQRHLL HLRERWEQQV SAADGKPGRQ SRKEVTQATQ PEAIPQGTNI 1200 TEEKPGRKRA EAKGNRSWSE ESLKPSDNEQ GLPVFSGSPP MKSLSSTSAG GKKQAQPSCA 1260 PASRPPAKQQ KIKENQKTDV LCADEEEDCQ AASLLQKYTD NSEKPSGKRL CKTKHLIPQE 1320 SRRGLPLTGE YYVENADGKV TVRRFRKRPE PSSDYDLSPA KQEPKPFDRL QQLLPASQST 1380 QLPCSSSPQE TTQSRPMPPE ARRLIVNKNA GETLLQRAAR LGYEEVVLYC LENKICDVNH 1440 RDNAGYCALH EACARGWLNI VRHLLEYGAD VNCSAQDGTR PLHDAVENDH LEIVRLLLSY 1500 GADPTLATYS GRTIMKMTHS ELMEKFLTAI ETQSSSSEEI VPSPPSPPPL PRIYKPCFVC 1560 QDKSSGYHYG VSACEGCKGF FRRSIQKNMV YTCHRDKNCI INKVTRNRCQ YCRLQKCFEV 1620 GMSKESVRND RNKKKKEVPK PECSESYTLT PEVGELIEKV RKAHQETFPA LCQLGKYTTN 1680 NSSEQRVSLD IDLWDKFSEL STKCIIKTVE FAKQLPGFTT LTIADQITLL KAACLDILIL 1740 RICTRYTPEQ DTMTFSDGLT LNRTQMHNAG FGPLTDLVFA FANQLLPLEM DDAETGLLSA 1800 ICLICGDRQD LEQPDRVDML QEPLLEALKV YVRKRRPSRP HMFPKMLMKI TDLRSISAKG 1860 AERVITLKME IPGSMPPLIQ EMLENSEGLD TLSGQPGGGG RDGGGLAPPP GSCSPSLSPS 1920 SNRSSPATHS P 1931 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-KW. GO:0003708; F:retinoic acid receptor activity; IEA:InterPro. GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. GO:0003707; F:steroid hormone receptor activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |