UniProt Accession

 SEP14_HUMAN; Q6ZU15; A6NCC2; B4DXD6 

Genbank Protein ID

 AK126048; AK301928; AC092647 

Genbank Nucleotide ID

 BAC86412.1; BAG63348.1 

Protein Name

 Septin-14 

Protein Synonyms/Alias

  

Gene Name

 SEPT14 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
195	NIIPLIAKADTISKN	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). 

Sequence Annotation

 NP_BIND 59 66 GTP (By similarity).
 NP_BIND 195 203 GTP (By similarity).
 BINDING 114 114 GTP; via amide nitrogen (By similarity).
 BINDING 249 249 GTP; via amide nitrogen and carbonyl
 BINDING 264 264 GTP (By similarity).  

Keyword

 Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 432 AA 

Protein Sequence

Gene Ontology

 GO:0031105; C:septin complex; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW. 

Interpro

 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase.
 IPR016491; Septin. 

Pfam

 PF00735; Septin 

SMART

  

PROSITE

  

PRINTS