CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002518
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-dehydroquinate synthase 
Protein Synonyms/Alias
  
Gene Name
 aroB 
Gene Synonyms/Alias
 b3389; JW3352 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
52LAPLYLDKVRGVLEQacetylation[1]
91VFTALLQKPHGRDTTacetylation[1]
142VDSSVGGKTAVNHPLacetylation[1]
151AVNHPLGKNMIGAFYacetylation[2]
298QRIITLLKRAGLPVNacetylation[1]
323LPHMLRDKKVLAGEMacetylation[1]
324PHMLRDKKVLAGEMRacetylation[1]
340ILPLAIGKSEVRSGVacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 
Functional Description
  
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Cobalt; Complete proteome; Cytoplasm; Lyase; NAD; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 362 AA 
Protein Sequence
MERIVVTLGE RSYPITIASG LFNEPASFLP LKSGEQVMLV TNETLAPLYL DKVRGVLEQA 60
GVNVDSVILP DGEQYKSLAV LDTVFTALLQ KPHGRDTTLV ALGGGVVGDL TGFAAASYQR 120
GVRFIQVPTT LLSQVDSSVG GKTAVNHPLG KNMIGAFYQP ASVVVDLDCL KTLPPRELAS 180
GLAEVIKYGI ILDGAFFNWL EENLDALLRL DGPAMAYCIR RCCELKAEVV AADERETGLR 240
ALLNLGHTFG HAIEAEMGYG NWLHGEAVAA GMVMAARTSE RLGQFSSAET QRIITLLKRA 300
GLPVNGPREM SAQAYLPHML RDKKVLAGEM RLILPLAIGK SEVRSGVSHE LVLNAIADCQ 360
SA 362 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:EcoliWiki.
 GO:0003856; F:3-dehydroquinate synthase activity; IDA:EcoliWiki.
 GO:0009073; P:aromatic amino acid family biosynthetic process; TAS:EcoliWiki.
 GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR016037; DHQ_synth_AroB. 
Pfam
  
SMART
  
PROSITE
  
PRINTS