UniProt Accession

 E9PI83_HUMAN; E9PI83 

Genbank Protein ID

 AC011495 

Genbank Nucleotide ID

  

Protein Name

 Protein arginine N-methyltransferase 1 

Protein Synonyms/Alias

  

Gene Name

 PRMT1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
92	AAKAGARKVIGIECS	ubiquitination	[1, 2, 3]

Reference

 [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Methyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 113 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0016275; F:[cytochrome c]-arginine N-methyltransferase activity; IEA:Compara.
 GO:0008469; F:histone-arginine N-methyltransferase activity; IEA:Compara.
 GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IEA:Compara.
 GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IEA:Compara.
 GO:0030519; F:snoRNP binding; IEA:Compara.
 GO:0034969; P:histone arginine methylation; IEA:GOC.
 GO:0001701; P:in utero embryonic development; IEA:Compara. 

Interpro

 IPR025799; Arg_MeTrfase.
 IPR010456; Ribosomal-L11_MeTrfase_PrmA. 

Pfam

 PF06325; PrmA 

SMART

  

PROSITE

  

PRINTS