UniProt Accession

 B4DI08_HUMAN; B4DI08 

Genbank Protein ID

 AK295353 

Genbank Nucleotide ID

 BAG58320.1 

Protein Name

 cDNA FLJ60091, highly similar to Hypoxia-inducible factor 1 alpha inhibitor(EC 1.14.11.16) 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
140	KFLYYDEKKMANFQN	ubiquitination	[1]
149	MANFQNFKPRSNREE	ubiquitination	[1, 2, 3]
165	KFHEFVEKLQDIQQR	ubiquitination	[1]
379	PLLNTMIKGRYN***	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 383 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR027445; FIH-1.
 IPR027452; FIH-1_domII.
 IPR003347; JmjC_dom. 

Pfam

  

SMART

 SM00558; JmjC 

PROSITE

 PS51184; JMJC 

PRINTS