UniProt Accession

 SNZ1_YEAST; Q03148; D6VZR9 

Genbank Protein ID

 Z49807; BK006946 

Genbank Nucleotide ID

 CAA89897.1; DAA09993.1 

Protein Name

 Pyridoxine biosynthesis protein SNZ1 

Protein Synonyms/Alias

 PDX1 homolog 1; p35 

Gene Name

 SNZ1 

Gene Synonyms/Alias

 YMR096W; YM6543.03 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
80	VSIPVMAKVRIGHFV	acetylation	[1]
161	GDVSEAVKHIRRITE	acetylation	[1]
177	IKACQQLKSEDDIAK	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Required for the production of pyridoxine (vitamin B6). May be involved in growth arrest and cellular response to nutrient limitation. Required for growth in the presence of low level of intracellular pyridoxine. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Pyridoxine biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 297 AA 

Protein Sequence

Gene Ontology

 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:InterPro.
 GO:0008615; P:pyridoxine biosynthetic process; IMP:SGD. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR011060; RibuloseP-bd_barrel.
 IPR001852; Snz1p/Sor1. 

Pfam

 PF01680; SOR_SNZ 

SMART

  

PROSITE

 PS01235; PDXS_SNZ_1
 PS51129; PDXS_SNZ_2 

PRINTS