CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028768
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 COP9 signalosome complex subunit 2 
Protein Synonyms/Alias
  
Gene Name
 Cops2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
290TEFEKILKTNHSNIMubiquitination[1]
323QVLIKLIKPYTRIHIubiquitination[1]
374LLELDHQKRGGARYTubiquitination[1]
385ARYTALDKWTNQLNSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA LSSFQKVLEL 60
EGEKGEWGFK ALKQMIKINF KLTNFPEMMN RYKQLLTYIR SAVTRNYSEK SINSILDYIS 120
TSKQNSDFLC QMDLLQEFYE TTLEALKDAK NDRLWFKTNT KLGKLYLERE EYGKLQKILR 180
QLHQSCQTDD GEDDLKKECG GKMHLREGEF EKAHTDFFEA FKNYDESGSP RRTTCLKYLV 240
LANMLMKSGI NPFDSQEAKP YKNDPEILAM TNLVSAYQNN DITEFEKILK TNHSNIMDDP 300
FIREHIEELL RNIRTQVLIK LIKPYTRIHI PFISKELNID VADVESLLVQ CILDNTIHGR 360
IDQVNQLLEL DHQKRGGARY TALDKWTNQL NSLNQAVVSK LA 402 
Gene Ontology
 GO:0008180; C:signalosome; IDA:MGI.
 GO:0003714; F:transcription corepressor activity; IDA:MGI.
 GO:0008283; P:cell proliferation; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0035914; P:skeletal muscle cell differentiation; IMP:MGI. 
Interpro
 IPR013143; PAM.
 IPR000717; PCI_dom.
 IPR011990; TPR-like_helical.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF01399; PCI 
SMART
 SM00753; PAM
 SM00088; PINT 
PROSITE
  
PRINTS