CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021498
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 YY1-associated protein 1 
Protein Synonyms/Alias
 Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated protein 2 
Gene Name
 YY1AP1 
Gene Synonyms/Alias
 HCCA2; YY1AP 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
148QKEVEKVKPQCKEVHubiquitination[1]
152EKVKPQCKEVHQTLIubiquitination[1]
589ARAFRCIKPAPVIHPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Enhances transcription activation by YY1. May play a role in cell cycle regulation. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 796 AA 
Protein Sequence
MEEEASRSAA ATNPGSRLTR WPPPDKREGS AVDPGKRRSL AATPSSSLPC TLIALGLRHE 60
KEANELMEDL FETFQDEMGF SNMEDDGPEE EERVAEPQAN FNTPQALRFE ELLANLLNEQ 120
HQIAKELFEQ LKMKKPSAKQ QKEVEKVKPQ CKEVHQTLIL DPAQRKRLQQ QMQQHVQLLT 180
QIHLLATCNP NLNPEASSTR ICLKELGTFA QSSIALHHQY NPKFQTLFQP CNLMGAMQLI 240
EDFSTHVSID CSPHKTVKKT ANEFPCLPKQ VAWILATSKV FMYPELLPVC SLKAKNPQDK 300
ILFTKAEDNK YLLTCKTARQ LTVRIKNLNM NRAPDNIIKF YKKTKQLPVL GKCCEEIQPH 360
QWKPPIEREE HRLPFWLKAS LPSIQEELRH MADGAREVGN MTGTTEINSD QGLEKDNSEL 420
GSETRYPLLL PKGVVLKLKP VADRFPKKAW RQKRSSVLKP LLIQPSPSLQ PSFNPGKTPA 480
QSTHSEAPPS KMVLRIPHPI QPATVLQTVP GVPPLGVSGG ESFESPAALP AMPPEARTSF 540
PLSESQTLLS SAPVPKVMMP SPASSMFRKP YVRRRPSKRR GARAFRCIKP APVIHPASVI 600
FTVPATTVKI VSLGGGCNMI QPVNAAVAQS PQTIPIATLL VNPTSFPCPL NQPLVASSVS 660
PLIVSGNSVN LPIPSTPEDK AHMNVDIACA VADGENAFQG LEPKLEPQEL SPLSATVFPK 720
VEHSPGPPPV DKQCQEGLSE NSAYRWTVVK TEEGRQALEP LPQGIQESLN NSSPGDLEEV 780
VKMEPEDATE EISGFL 796 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS