CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041603
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycine--tRNA ligase 
Protein Synonyms/Alias
 RCG52516 
Gene Name
 Gars 
Gene Synonyms/Alias
 rCG_52516 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
88DRAVAELKARKRVLEubiquitination[1]
97RKRVLEAKELALQPKacetylation[2]
97RKRVLEAKELALQPKubiquitination[1]
186KTSGHVDKFADFMVKubiquitination[1]
193KFADFMVKDVKNGECacetylation[2]
208FRADHLLKAHLQKLMacetylation[2]
213LLKAHLQKLMSDKKCacetylation[2]
408RIYLYLTKVGISPDKubiquitination[1]
490VVQFEPNKGAVGKAYacetylation[2]
722FEGQETGKKETVEE*ubiquitination[1]
723EGQETGKKETVEE**ubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 728 AA 
Protein Sequence
MPCLLPTLLR ATRAALLLQS PRVVAAPASQ RLLSAPAQPA ASPSSMDSAE ELLAPLRLAV 60
RQQGDFVRKL KEDKAPQVDV DRAVAELKAR KRVLEAKELA LQPKDDIVDR AKMEDTLKRR 120
FFYDQAFAIY GGVSGLYDFG PVGCALKNNI IQTWRQHFIQ EEQILEIDCT MLTPEPVLKT 180
SGHVDKFADF MVKDVKNGEC FRADHLLKAH LQKLMSDKKC SAEKKSEMES VLAQLDNYGQ 240
QELADLFVNY NVKSPTTGND LSPPVPFNLM FQTFIGPGGN MPGYLRPETA QGIFLNFKRL 300
LEFNQGKLPF AAAQIGNSFR NEISPRSGLI RVREFTMAEI EHFVDPTEKD HPKFPSVADL 360
YLYLYSAKAQ VTGQSARKMR LGDAVEQGVI NNSVLGYFIG RIYLYLTKVG ISPDKLRFRQ 420
HMENEMAHYA CDCWDAESKT SYGWIEIVGC ADRSCYDLSC HARATKVPLV AEKPLKEPKT 480
VNVVQFEPNK GAVGKAYKKD AKLVLEYLGA CDECYITEME LLLSEKGEFT IETEGKTFQL 540
TKDMVSVKRF QKTLHVEEVV PSVIEPSFGL GRIMYTILEH TFHVREGDEQ RTFFSFPAVV 600
APFKCSVLPL SQNQEFMPFV KELSEALTRN GVSHKVDDSS GSIGRRYART DEIGVAFGIT 660
IDFDTVNKTP HTATLRDRDS MRQIRAEVSE LPSVVRDLAN GNITWADVEA RYPLFEGQET 720
GKKETVEE 728 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0030141; C:secretory granule; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004820; F:glycine-tRNA ligase activity; IEA:Compara.
 GO:0015966; P:diadenosine tetraphosphate biosynthetic process; IEA:Compara.
 GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR002314; aa-tRNA-synt_IIb_cons-dom.
 IPR006195; aa-tRNA-synth_II.
 IPR004154; Anticodon-bd.
 IPR027031; Gly-tRNA_synthase/POLG2.
 IPR009068; S15_NS1_RNA-bd.
 IPR002315; tRNA-synt_gly.
 IPR000738; WHEP-TRS. 
Pfam
 PF03129; HGTP_anticodon
 PF00587; tRNA-synt_2b
 PF00458; WHEP-TRS 
SMART
 SM00991; WHEP-TRS 
PROSITE
 PS50862; AA_TRNA_LIGASE_II
 PS00762; WHEP_TRS_1
 PS51185; WHEP_TRS_2 
PRINTS
 PR01043; TRNASYNTHGLY.