UniProt Accession

 TSTD2_HUMAN; Q5T7W7; A6NMJ4; A8K584; Q6ZQZ6; Q8IYM3; Q8WY73; Q96ML6; Q96MU1 

Genbank Protein ID

 AF258575; AK056453; AK056752; AK128615; AK291199; AL162385; AL162385; CH471105; BC035604 

Genbank Nucleotide ID

 AAG23778.1; BAB71188.1; BAB71271.1; BAC87530.1; BAF83888.1; CAI12859.1; CAI12860.1; EAW58848.1; AAH35604.1 

Protein Name

 Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 

Protein Synonyms/Alias

 Rhodanese domain-containing protein 2 

Gene Name

 TSTD2 

Gene Synonyms/Alias

 C9orf97; PP4189 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
26	RFSDLDLKDMSLINP	ubiquitination	[1]
217	NGTVGGSKLATRLYV	ubiquitination	[1, 2]
246	KDDFKTSKGGAHCFP	ubiquitination	[2]
272	PMGISPKKISYKKPG	ubiquitination	[2]
277	PKKISYKKPGIHLSP	ubiquitination	[2]
317	CRNFYESKIGRFQGC	ubiquitination	[1, 2, 3]
331	CLAPDIRKFSYFPSY	ubiquitination	[2]
399	PDGFYKGKLFVFDER	ubiquitination	[2]
476	GPMQDSFKEECECTA	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

 DOMAIN 301 396 Rhodanese.
 ACT_SITE 355 355 Cysteine persulfide intermediate (By  

Keyword

 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 516 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001763; Rhodanese-like_dom. 

Pfam

 PF00581; Rhodanese 

SMART

 SM00450; RHOD 

PROSITE

 PS50206; RHODANESE_3 

PRINTS