CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019285
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alpha/beta hydrolase domain-containing protein 17A 
Protein Synonyms/Alias
  
Gene Name
 ABHD17A 
Gene Synonyms/Alias
 C19orf27; FAM108A1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
226RVAFPDTKKTYCFDAubiquitination[1]
227VAFPDTKKTYCFDAFubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 ACT_SITE 190 190 Charge relay system (By similarity).
 ACT_SITE 255 255 Charge relay system (By similarity).
 ACT_SITE 284 284 Charge relay system (By similarity).
 MOD_RES 307 307 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Hydrolase; Phosphoprotein; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 310 AA 
Protein Sequence
MNGLSLSELC CLFCCPPCPG RIAAKLAFLP PEATYSLVPE PEPGPGGAGA APLGTLRASS 60
GAPGRWKLHL TERADFQYSQ RELDTIEVFP TKSARGNRVS CMYVRCVPGA RYTVLFSHGN 120
AVDLGQMSSF YIGLGSRLHC NIFSYDYSGY GASSGRPSER NLYADIDAAW QALRTRYGIS 180
PDSIILYGQS IGTVPTVDLA SRYECAAVVL HSPLTSGMRV AFPDTKKTYC FDAFPNIEKV 240
SKITSPVLII HGTEDEVIDF SHGLALYERC PKAVEPLWVE GAGHNDIELY SQYLERLRRF 300
ISQELPSQRA 310 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS