UniProt Accession

 ARPC4_YEAST; P33204; D6VXS3 

Genbank Protein ID

 X74152; S53418; Z28013; AY558348; BK006944 

Genbank Nucleotide ID

 AAB24905.1; CAA81848.1; AAS56674.1; DAA09143.1 

Protein Name

 Actin-related protein 2/3 complex subunit 4 

Protein Synonyms/Alias

 Arp2/3 complex 20 kDa; p20-ARC 

Gene Name

 ARC19 

Gene Synonyms/Alias

 YKL013C; YKL166 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
90	IEQILVHKFTRFLEQ	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). 

Sequence Annotation

  

Keyword

 Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 171 AA 

Protein Sequence

Gene Ontology

 GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
 GO:0005885; C:Arp2/3 protein complex; IDA:SGD.
 GO:0005198; F:structural molecule activity; IMP:SGD.
 GO:0000147; P:actin cortical patch assembly; IMP:SGD.
 GO:0030041; P:actin filament polymerization; IEA:InterPro.
 GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
 GO:0000001; P:mitochondrion inheritance; TAS:SGD. 

Interpro

 IPR008384; ARPC4. 

Pfam

 PF05856; ARPC4 

SMART

  

PROSITE

  

PRINTS