CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035935
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NEDD4-binding protein 2-like 2 
Protein Synonyms/Alias
  
Gene Name
 N4BP2L2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
9SYGEIEGKFLGPREEubiquitination[1]
49DFHRIQEKTGNDWVPubiquitination[1]
374EVRERCWKDHCMDKHubiquitination[1]
396NQQFQEEKLNKLQKLubiquitination[1, 2, 3]
399FQEEKLNKLQKLLILubiquitination[1]
402EKLNKLQKLLILLRGubiquitination[1]
415RGLPGSGKTTLSRILubiquitination[1]
509HEPETWWKFDPEELEubiquitination[1]
517FDPEELEKRNKHGVSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 709 AA 
Protein Sequence
MSYGEIEGKF LGPREEVTSE PRCKKLKSTT ESYVFHNHSN ADFHRIQEKT GNDWVPVTII 60
DVRGHSYLQE NKIKTTDLHR PLHDEMPGNR PDVIESIDSQ VLQEARPPLV SADDEIYSTS 120
KAFIGPIYKP PEKKKRNEGR NEAHVLNGIN DRGGQKEKQK FNSEKSEIDN ELFQFYKEIE 180
ELEKEKDGFE NSCKESEPSQ EQFVPFYEGH NNGLLKPDEE KKDLSNKAMP SHCDYQQNLG 240
NEPDKYPCNG QVIPTFCDTS FTSFRPEWQS VYPFIVPYGP PLPSLNYHLN IQRFSGPPNP 300
PSNIFQAQDD SQIQNGYYVN NCHVNWNCMT FDQNNEYTDC SENRSSVHPS GNGCSMQDRY 360
VSNGFCEVRE RCWKDHCMDK HNGTDRFVNQ QFQEEKLNKL QKLLILLRGL PGSGKTTLSR 420
ILLGQNRDGI VFSTDDYFHH QDGYRYNVNQ LGDAHDWNQN RAKQAIDQGR SPVIIDNTNI 480
QAWEMKPYVE VAIGKGYRVE FHEPETWWKF DPEELEKRNK HGVSRKKIAQ MLDRYEYQMS 540
ISIVMNSVEP SHKSTQRPPP PQGRQRERVL KKTGHRLSKT KQKRNRKRNK KQNSQNRIME 600
ENSLEFLSDL TPGDQDPSQS EEEDIEKTRR ESEYPFIDGL QNEVGDFVTG YKEKRWKNKD 660
PKDSFQNVMS IVELDNTPKN YLSKEGDNLF VSLLLRPNEI SVTCPILTQ 709 
Gene Ontology
  
Interpro
 IPR026568; NEDD4-bind_pro_2-like_2.
 IPR027417; P-loop_NTPase. 
Pfam
  
SMART
  
PROSITE
  
PRINTS