| Tag | Content |
|---|
| CPLM ID | CPLM-018610 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and SOCS box protein 9 |
Protein Synonyms/Alias | ASB-9 |
Gene Name | Asb9 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 284 | LLLPEDLKRFLLHL* | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A (By similarity). |
Sequence Annotation | REPEAT 31 60 ANK 1.
REPEAT 64 93 ANK 2.
REPEAT 97 126 ANK 3.
REPEAT 129 158 ANK 4.
REPEAT 162 191 ANK 5.
REPEAT 194 223 ANK 6.
DOMAIN 236 290 SOCS box. |
Keyword | ANK repeat; Complete proteome; Mitochondrion; Reference proteome; Repeat; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 290 AA |
Protein Sequence | MDGEQRGRSD RPGGSPHLPF LSNPLMGDVV SDWSPLHDAA IHGCLLTLRN LISQGWPVNI 60
ITADHVSPLH EACLRGHLSC ASVLLSHGAQ VNGMTIDWRT PLFNACVSGS QDCVNLLLQH 120
GATPHPETEL ASPIHEAAKR GYVKCIESLA AHGANIDYNI SHLGTPLYVA CKNQQVACAK 180
KLLESGVSVN QGKGLDSPLH VVARMSSVEL VHLLMDFGAN AQAKNADGKR PVDLVPLESP 240
LIQIFLQNEG PQSLRQLCRL RIRKCFGIRQ HHKISELLLP EDLKRFLLHL 290 |
Gene Ontology | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:Compara. GO:0035556; P:intracellular signal transduction; IEA:InterPro. GO:0045732; P:positive regulation of protein catabolic process; IEA:Compara. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |