| Tag | Content |
|---|
| CPLM ID | CPLM-014434 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Endophilin-A3 |
Protein Synonyms/Alias | Endophilin-3; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3; SH3p13 |
Gene Name | Sh3gl3 |
Gene Synonyms/Alias | Sh3d2c; Sh3d2c2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 82 | SKLRGQVKATGYPQT | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). |
Sequence Annotation | DOMAIN 18 249 BAR.
DOMAIN 285 344 SH3.
REGION 1 21 Membrane-binding amphipathic helix (By
REGION 60 87 Required for dimerization upon membrane
REGION 218 254 Interaction with ARC (By similarity). |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Lipid-binding; Membrane; Reference proteome; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 347 AA |
Protein Sequence | MSVAGLKKQF HKASQLFSEK ISGAEGTKLD EEFLNMEKKI DITSKAVAEI LSKATEYLQP 60
NPAYRAKLGM LNTVSKLRGQ VKATGYPQTE GLLGDCMLKY GKELGEDSAF GNSLVDVGEA 120
LKLMAEVKDS LDINVKQTFI DPLQLLQDKD LKEIGHHLRK LEGRRLDYDY KKRRVGKIPE 180
EEIRQAVEKF EESKELAERS MFNFLENDVE QVSQLAVFVE AALDYHRQST EILQELQSKL 240
ELRISLASKV PKREFMPKPV NMSSTDANGV GPSSSSKTPG TDTPADQPCC RGLYDFEPEN 300
EGELGFKEGD IITLTNQIDE NWYEGMLRGE SGFFPINYVE VIVPLPP 347 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |