| Tag | Content |
|---|
| CPLM ID | CPLM-001641 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Amyloid beta A4 precursor protein-binding family B member 3 |
Protein Synonyms/Alias | Protein Fe65-like 2; Fe65L2 |
Gene Name | APBB3 |
Gene Synonyms/Alias | FE65L2 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 138 | EEDLAPGKSSIAVNN | ubiquitination | [1] | | 176 | NMLMILKKDAMSLVN | ubiquitination | [1] | | 207 | VWGVGSSKGRDSPIS | ubiquitination | [1] | | 461 | PLPLPLLKGGVGGAG | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May modulate the internalization of beta-amyloid precursor protein. |
Sequence Annotation | DOMAIN 29 61 WW.
DOMAIN 113 280 PID 1.
DOMAIN 285 440 PID 2. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Polymorphism; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 486 AA |
Protein Sequence | MLGKDYMLAI ILVNCDDDLW GDHSLEVEAG LPPGWRKIHD AAGTYYWHVP SGSTQWQRPT 60
WELGDAEDPG TGTEGIWGLR PPKGRSFSSL ESSLDRSNSL SWYGGESYIQ SMEPGAKCFA 120
VRSLGWVEVP EEDLAPGKSS IAVNNCIQQL AQTRSRSQPP DGAWGEGQNM LMILKKDAMS 180
LVNPLDHSLI HCQPLVHIRV WGVGSSKGRD SPISAPARDF AFVASDKDSC MLKCHVFCCD 240
VPAKAIASAL HGLCAQILSE RVEVSGDASC CSPDPISPED LPRQVELLDA VSQAAQKYEA 300
LYMGTLPVTK AMGMDVLNEA IGTLTARGDR NAWVPTMLSV SDSLMTAHPI QAEASTEEEP 360
LWQCPVRLVT FIGVGRDPHT FGLIADLGRQ SFQCAAFWCQ PHAGGLSEAV QAACMVQYQK 420
CLVASAARGK AWGAQARARL RLKRTSSMDS PGGPLPLPLL KGGVGGAGAT PRKRGVFSFL 480
DAFRLKPSLL HMP 493 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |