UniProt Accession

 E9PQZ2_HUMAN; E9PQZ2 

Genbank Protein ID

 AP000806; AP001318 

Genbank Nucleotide ID

  

Protein Name

 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 

Protein Synonyms/Alias

  

Gene Name

 ST3GAL4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
140	SLGDAINKYDVVIRL	ubiquitination	[1]
162	YEGDVGSKTTMRLFY	ubiquitination	[2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Glycosyltransferase; Golgi apparatus; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; IEA:Compara.
 GO:0047288; F:monosialoganglioside sialyltransferase activity; IEA:Compara.
 GO:0006486; P:protein glycosylation; IEA:InterPro. 

Interpro

 IPR001675; Glyco_trans_29. 

Pfam

 PF00777; Glyco_transf_29 

SMART

  

PROSITE

  

PRINTS