CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038930
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Herc6 
Protein Synonyms/Alias
  
Gene Name
 Herc6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
56SRGQLGQKSPQSTKRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome; Repeat; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1000 AA 
Protein Sequence
MYFTWAPGRR QPRRLEAGTG LKLLKAASGE RHSLLLFSNH RVYSCGDNSR GQLGQKSPQS 60
TKRPEPIQAL STVHIDLVSC GKEHSVAVCH QGRVFTWGAG SEGQLGIGES KEISFMPTKI 120
NSLAGIKIIQ VSCGHYHSLA LSEDGQVFSW GSNRQGQLGL GNNLCSQASP QKVKSLEGIP 180
LAQVAAGGTH SFALSLMGTS FGWGNNRSGQ LALSGNSAKA EQIYKPHSIG ALKTLNVVYI 240
SCGYEHTSVL TEDGQVFTFG GSSSEQLQHS PRSGRGGPQL IEGIGGHVSQ IECGSYHTIA 300
YVYTTGQVVS LGRGPSCTSN ATHQEAACSD VTCLLSAKDL VDIEVKDIFA GAHANFVTTC 360
RVSHTRSTSV SMKILPEIIR ITQPLVKKWR AAKKGKVHED AKREISLIFS SPACLTASFL 420
KKRDAGENNF INVDLKLARD VFKMLTAEKW ISSLITTCLE ETLLRGLPYS SPHQEALLVF 480
LLLPECSIMQ DPKNWKTLAF EFASAIHKMR SKSLTFLRNW WASLEVSSLN SLVQMLKKTI 540
VSQLHNEVPK MEDTSNLKVL LEVMKEVHEA NCQLPENAFI MNDIFNFNTE ANGMFIQYNI 600
LACNKYCDEV RVFNDFPFIL DLPSKIILMK HDSSVKLSDE VKVAASPEKM GCPFFILKVR 660
RSHLVEDTLR QLRQAEDFDL RKTLSVGFIN EIRPEGGGVS SEFFHCIFEE MTDPKYEMFM 720
YPENGSNMWF PVNPKFEKSR YFLFGILCGL SLNNLNVINL SFPLALYKKL LEQKPSLEDL 780
KDLSLLLGRN LQEVLNCEAG VIEELHMYFS IYWDQRDVDL IPDGISVPVN ETNKRDYVSK 840
CVDYIFNISI KTIYDEFHRG FYKVCNRDSI RHFQPEELMA AIIGNPTCDW KQFENNSKYE 900
NGYSKSHPTI LLFWKAFHEL TLDEKKKFLL FLTGCDRLHV KGLQNEGIRF RCPEVFSERD 960
NPRSLTCHSI LDLPKYSTMR RMKEALQVAI NNNKGFISPE 1000 
Gene Ontology
 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0005634; C:nucleus; IBA:RefGenome.
 GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
 GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. 
Interpro
 IPR000569; HECT.
 IPR009091; RCC1/BLIP-II.
 IPR000408; Reg_chr_condens. 
Pfam
 PF00632; HECT
 PF00415; RCC1 
SMART
 SM00119; HECTc 
PROSITE
 PS50237; HECT
 PS00626; RCC1_2
 PS50012; RCC1_3 
PRINTS
 PR00633; RCCNDNSATION.