UniProt Accession

 RL18_ECOLI; P0C018; P02419; Q2M6W9 

Genbank Protein ID

 X01563; U18997; U00096; AP009048 

Genbank Nucleotide ID

 CAA25721.1; AAA58101.1; AAC76329.1; BAE77987.1 

Protein Name

 50S ribosomal protein L18 

Protein Synonyms/Alias

  

Gene Name

 rplR 

Gene Synonyms/Alias

 b3304; JW3266 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
56	VAASTVEKAIAEQLK	acetylation	[1]
63	KAIAEQLKYTGNKDA	acetylation	[1]
68	QLKYTGNKDAAAAVG	acetylation	[1]
76	DAAAAVGKAVAERAL	acetylation	[1]
85	VAERALEKGIKDVSF	acetylation	[1]
88	RALEKGIKDVSFDRS	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 This is one of the proteins that mediates the attachment of the 5S rRNA subcomplex onto the large ribosomal subunit where it forms part of the central protuberance. Binds stably to 5S rRNA; increases binding abilities of L5 in a cooperative fashion; both proteins together confer 23S rRNA binding. The 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. 

Sequence Annotation

 REGION 1 17 Required for binding of the 5S  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 117 AA 

Protein Sequence

Gene Ontology

 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0019843; F:rRNA binding; IEA:HAMAP.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:HAMAP. 

Interpro

 IPR005484; Ribosomal_L18/L5.
 IPR004389; Ribosomal_L18_bac-type. 

Pfam

 PF00861; Ribosomal_L18p 

SMART

  

PROSITE

  

PRINTS