UniProt Accession

 ATPB_ECOLI; P0ABB4; P00824; Q2M850 

Genbank Protein ID

 X01631; V00267; M25464; J01594; V00311; V00312; L10328; U00096; AP009048 

Genbank Nucleotide ID

 CAA25782.1; CAA23527.1; AAA83875.1; AAA24737.1; CAA23594.1; CAA23598.1; AAA62084.1; AAC76755.1; BAE77556.1 

Protein Name

 ATP synthase subunit beta 

Protein Synonyms/Alias

 ATP synthase F1 sector subunit beta; F-ATPase subunit beta 

Gene Name

 atpD 

Gene Synonyms/Alias

 papB; uncD; b3732; JW3710 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
70	LRRGLDVKDLEHPIE	acetylation	[1, 2, 3]
82	PIEVPVGKATLGRIM	acetylation	[2, 3]
99	LGEPVDMKGEIGEEE	acetylation	[3]
142	DLMCPFAKGGKVGLF	acetylation	[2, 3]
156	FGGAGVGKTVNMMEL	acetylation	[3]
202	TDSNVIDKVSLVYGQ	acetylation	[3]
230	TGLTMAEKFRDEGRD	acetylation	[3]
372	LQRYQELKDIIAILG	acetylation	[3]
417	VFTGSPGKYVSLKDT	acetylation	[3]
422	PGKYVSLKDTIRGFK	acetylation	[3]

Reference

 [1] The diversity of lysine-acetylated proteins in Escherichia coli.
 Yu BJ, Kim JA, Moon JH, Ryu SE, Pan JG.
 J Microbiol Biotechnol. 2008 Sep;18(9):1529-36. [PMID: 18852508]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [3] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. 

Sequence Annotation

 NP_BIND 150 157 ATP (By similarity).  

Keyword

 3D-structure; ATP synthesis; ATP-binding; Cell inner membrane; Cell membrane; CF(1); Complete proteome; Direct protein sequencing; Hydrogen ion transport; Hydrolase; Ion transport; Membrane; Nucleotide-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 460 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IMP:EcoliWiki.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:HAMAP.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IMP:EcoCyc.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0042777; P:plasma membrane ATP synthesis coupled proton transport; IEA:HAMAP. 

Interpro

 IPR003593; AAA+_ATPase.
 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR005722; ATPase_F1-cplx_bsu.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR024034; ATPase_F1_bsu/V1_C.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 

SMART

 SM00382; AAA 

PROSITE

 PS00152; ATPASE_ALPHA_BETA 

PRINTS