CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011578
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosome biogenesis protein BRX1 
Protein Synonyms/Alias
  
Gene Name
 BRX1 
Gene Synonyms/Alias
 YOL077C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
6**MSSIYKALAGKSKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Required for biogenesis of the 60S ribosomal subunit. 
Sequence Annotation
 DOMAIN 31 232 Brix.
 MOD_RES 285 285 Phosphoserine.  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 291 AA 
Protein Sequence
MSSIYKALAG KSKDNKSEKK QGNVKQFMNK QRTLLISSRG VNYRHRHLIQ DLSGLLPHSR 60
KEPKLDTKKD LQQLNEIAEL YNCNNVLFFE ARKHQDLYLW LSKPPNGPTI KFYIQNLHTM 120
DELNFTGNCL KGSRPVLSFD QRFESSPHYQ LIKELLVHNF GVPPNARKSK PFIDHVMSFS 180
IVDDKIWVRT YEISHSTKNK EEYEDGEEDI SLVEIGPRFV MTVILILEGS FGGPKIYENK 240
QYVSPNVVRA QIKQQAAEEA KSRAEAAVER KIKRRENVLA ADPLSNDALF K 291 
Gene Ontology
 GO:0005730; C:nucleolus; IPI:SGD.
 GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
 GO:0008097; F:5S rRNA binding; IPI:SGD.
 GO:0042134; F:rRNA primary transcript binding; IPI:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IPI:SGD. 
Interpro
 IPR004154; Anticodon-bd.
 IPR007109; Brix.
 IPR026532; BRX1. 
Pfam
 PF04427; Brix 
SMART
 SM00879; Brix 
PROSITE
 PS50833; BRIX 
PRINTS