CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022904
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gamma-tubulin complex component 4 
Protein Synonyms/Alias
 GCP-4; hGCP4; Gamma-ring complex protein 76 kDa; h76p; hGrip76 
Gene Name
 TUBGCP4 
Gene Synonyms/Alias
 76P; GCP4 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
233GIGGLTGKQLRELQDubiquitination[1]
315AAELHRLKQQPLFSLubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
 Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. 
Sequence Annotation
  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Microtubule; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 667 AA 
Protein Sequence
MIHELLLALS GYPGSIFTWN KRSGLQVSQD FPFLHPSETS VLNRLCRLGT DYIRFTEFIE 60
QYTGHVQQQD HHPSQQGQGG LHGIYLRAFC TGLDSVLQPY RQALLDLEQE FLGDPHLSIS 120
HVNYFLDQFQ LLFPSVMVVV EQIKSQKIHG CQILETVYKH SCGGLPPVRS ALEKILAVCH 180
GVMYKQLSAW MLHGLLLDQH EEFFIKQGPS SGNVSAQPEE DEEDLGIGGL TGKQLRELQD 240
LRLIEEENML APSLKQFSLR VEILPSYIPV RVAEKILFVG ESVQMFENQN VNLTRKGSIL 300
KNQEDTFAAE LHRLKQQPLF SLVDFEQVVD RIRSTVAEHL WKLMVEESDL LGQLKIIKDF 360
YLLGRGELFQ AFIDTAQHML KTPPTAVTEH DVNVAFQQSA HKVLLDDDNL LPLLHLTIEY 420
HGKEHKDATQ AREGPSRETS PREAPASGWA ALGLSYKVQW PLHILFTPAV LEKYNVVFKY 480
LLSVRRVQAE LQHCWALQMQ RKHLKSNQTD AIKWRLRNHM AFLVDNLQYY LQVDVLESQF 540
SQLLHQINST RDFESIRLAH DHFLSNLLAQ SFILLKPVFH CLNEILDLCH SFCSLVSQNL 600
GPLDERGAAQ LSILVKGFSR QSSLLFKILS SVRNHQINSD LAQLLLRLDY NKYYTQAGGT 660
LGSFGM 666 
Gene Ontology
 GO:0005813; C:centrosome; IDA:UniProtKB.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0008274; C:gamma-tubulin ring complex; NAS:UniProtKB.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0000922; C:spindle pole; IEA:InterPro.
 GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
 GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
 GO:0007020; P:microtubule nucleation; NAS:UniProtKB.
 GO:0006461; P:protein complex assembly; NAS:ProtInc. 
Interpro
 IPR007259; Spc97_Spc98. 
Pfam
 PF04130; Spc97_Spc98 
SMART
  
PROSITE
  
PRINTS