| Tag | Content |
|---|
| CPLM ID | CPLM-008812 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein ASI3 |
Protein Synonyms/Alias | Amino acid sensor-independent protein 3 |
Gene Name | ASI3 |
Gene Synonyms/Alias | YNL008C; N2874 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 386 | PEDLLSRKEMTTDSQ | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Negative regulator of SPS-sensor signaling. Together with ASI1 and ASI2, prevents the unprocessed precursor forms of STP1 and STP2 that escape cytoplasmic anchoring from inducing SPS- sensor-regulated genes in the absence of inducing signals. |
Sequence Annotation | ZN_FING 624 664 RING-type; atypical.
CARBOHYD 24 24 N-linked (GlcNAc...) (Potential).
CARBOHYD 34 34 N-linked (GlcNAc...) (Potential).
CARBOHYD 46 46 N-linked (GlcNAc...) (Potential).
CARBOHYD 66 66 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Membrane; Metal-binding; Nucleus; Reference proteome; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 676 AA |
Protein Sequence | MSTNILQHVK QLLHNRDVFS FFHNKTGNLN YLDNTTQKPE VFVSPNSTIV SAPTLDSFQA 60
LMEKGNFTTL QLAKVGIRMF FSYSVSKYAV LCFSTAIILN RLTVMSSLRS NSTNIRLPLW 120
SKTLLHLVAT LSLVKALLQI LSQFGLMHEL HVSDTDFYAL SVYLFVALSD CIEIFISSTT 180
NVPSLICSDF SIWGLSLNLY IISKMPAGQQ HIGDNVELLG AVFHRLVIHL VELFHIRAYR 240
LCGEVILNAG FFTAFVTRTY LNGLDFINIC LIHNYFPGFF YISTILLASI GIFLKALFTS 300
NPFRSLYSRY KNLEKWWRSN NYNGEEEFNE IALSLCLLLT SNDYKIFKKS DNVKSVDEVA 360
AFSNSYVVSG HLNQLQSTPE DLLSRKEMTT DSQLPGFART YLGLFELVRT IILTYSRLLK 420
NLLWSKNFES SIDKKPRVGK RKKRDLNKYV TEKNYKKFLY KPDVKELNIE SDLRSLELLL 480
PEDDSSKDYF PPRKIDESVS DEEFDSDMES QLIIDEEKEL THLSSNAVDS DDLEEIAWNI 540
SMWSILNYEM DVHNKVNGPL TRSQYGKRNP QGVLVDVVIE RLLHHTNSRY MYKRLNMKDD 600
DKLEFKFDFA FDSCDEVEEM DLSCLICKVN KRNIVTWPCR CLALCDDCRI SLGYKGFATC 660
VSCDSEVKGY SKLNIV 676 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IGI:SGD. GO:0016021; C:integral to membrane; ISM:SGD. GO:0005637; C:nuclear inner membrane; IDA:SGD. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004842; F:ubiquitin-protein ligase activity; IGI:SGD. GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |