CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040551
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Agl 
Protein Synonyms/Alias
  
Gene Name
 Agl 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
17LLLNEMEKLEKTLFRacetylation[1]
17LLLNEMEKLEKTLFRubiquitination[2]
61GEAFNREKFRSLDWEubiquitination[2]
151ESRLRVAKESGYNMIubiquitination[2]
269ADGKYREKGVPALIEubiquitination[2]
286QHMNCIRKIIWEDIFubiquitination[2]
334SEPKEHLKIIQDPEYacetylation[1, 3]
492ICWGDSVKLRYGNKPubiquitination[2]
511YLWAHMKKYTEITATubiquitination[2]
679AEERFYTKWNPGASPubiquitination[2]
761PKTSFYSKEVPQMCIubiquitination[2]
787RTIERNTKPYKKDENubiquitination[2]
791RNTKPYKKDENSINGubiquitination[2]
875TQFSSHFKSGSLAVDubiquitination[2]
889DNADPILKIPFASIAubiquitination[2]
1176PNGLDILKCPVSRMYubiquitination[2]
1262NCGTWMDKMGESDRAubiquitination[2]
1407ALEIAEKKLLGPLGMubiquitination[2]
1467RAKLYFSKMMGPETAubiquitination[2]
1482AKTVFLVKNVLSRHYubiquitination[2]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Circadian acetylome reveals regulation of mitochondrial metabolic pathways.
 Masri S, Patel VR, Eckel-Mahan KL, Peleg S, Forne I, Ladurner AG, Baldi P, Imhof A, Sassone-Corsi P.
 Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3339-44. [PMID: 23341599] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1532 AA 
Protein Sequence
MEHSKQIRIL LLNEMEKLEK TLFRLEQGFE LQFRLGPTLQ GKAVTVYTNY PLPGEAFNRE 60
KFRSLDWENP TEREDDSDKY CKLHLQQSGS FQYYFLQGNE KSGGGYIVVD PILRIGVDNH 120
VLPLDCVTLQ TFLAKCLGPF DEWESRLRVA KESGYNMIHF TPLQTLGLSR SCYSLADQLE 180
LNPDFSRPSK RYTWSDVGQL VEKLKREWNI LCITDVVYNH TATNSKWILE HPESAYNLVN 240
SPHLKPAWVL DRALWHFSCD VADGKYREKG VPALIENDQH MNCIRKIIWE DIFPRIQLWE 300
FFQVDVHKAV EQFRRLLSQE NRRVTKSEPK EHLKIIQDPE YRRRGCAVDM DTALATFIPH 360
DNGPAAIEEC CNWFRKRLEE LNSEKHHLTS CHQEQAVNCL LGNVFYERLA GHGPKLGPVT 420
RKYPLVTRYF TFPFGEMALS AEEALIHLPD KACFLMAHNG WVMGDDPLRN FAEPGSDVYL 480
RRELICWGDS VKLRYGNKPE DCPYLWAHMK KYTEITATHF QGVRLDNCHS TPLHVAEYML 540
DAARKLQPNL YVVAELFTGS EELDNIFVTR LGISSLIREA MSAYNSHEEG RLVYRYGGEP 600
VGSFVQPCLR PLMPAIAHAL FMDITHDNEC PIVHRSAYDA LPSTTVVSMA CCASGSTRGY 660
DELVPHQISV VAEERFYTKW NPGASPADTG DVNVHSGIIA ARCAINRLHQ ELGAKGFIQV 720
YVDQVDEDIV AVTRHSPSIH QSVVAVSRTA FRNPKTSFYS KEVPQMCIPG KIEEVVLEAR 780
TIERNTKPYK KDENSINGMP NMTVELREHI QLHESKIVRQ AGVATKGPNE YIQEIEFENL 840
SPGSVIIFRV SLDPHAQVAV GILRNHLTQF SSHFKSGSLA VDNADPILKI PFASIASKLT 900
LAELNQVLYR CESEEQEDGG GCYDIPNWSS LKYAGLQGLM SVLAEIRPKN DLGHPFCENL 960
RSGDWMIDYV SGRLISRSGS IAEVGKWLQA MFFYLKQIPR YLIPCYFDAI LIGAYTTLLD 1020
VAWKQMSSFV QNGSTFVKHL SLGSVQMCGV GKCPCLPLLS PSLLDVPCRL NEITKEKEQC 1080
CASLAAGLPH FSSGLFRCWG RDTFIALRGM LLVTGRYLEA RNIILAFAST LRHGLIPNLL 1140
GEGTYARYNC RDAVWWWLQC IQDYCRTVPN GLDILKCPVS RMYPTDDSAP LPAGTLDQPL 1200
FEVIQEAMQR HMQGIQFRER NAGPQIDRNM KDEGFNITAG IDEETGFVYG GNRFNCGTWM 1260
DKMGESDRAR NRGIPATPRD GSAVEIVGLC KSAVRWLLEL SKKNIFPYHE VRVKRHGKVV 1320
AVSYDEWNRK IQNNFEKLFH VSEDPSDPNE KHPNLVHKRG IYKDSYGASS PWCDYQLRPN 1380
FTIAMVVAPE LFTAEKAWKA LEIAEKKLLG PLGMKTLDPD DMVYCGVYDN ALDNDNYNLA 1440
RGFNYHQGPE WLWPIGYFLR AKLYFSKMMG PETAAKTVFL VKNVLSRHYV HLERSPWKGL 1500
PELTNENGQY CPFSCETQAW SMAVVLETLY DL 1532 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0016234; C:inclusion body; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0016529; C:sarcoplasmic reticulum; IEA:Compara.
 GO:0004134; F:4-alpha-glucanotransferase activity; IBA:RefGenome.
 GO:0004135; F:amylo-alpha-1,6-glucosidase activity; IBA:RefGenome.
 GO:0030247; F:polysaccharide binding; IDA:MGI.
 GO:0031593; F:polyubiquitin binding; IDA:MGI.
 GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
 GO:0005980; P:glycogen catabolic process; IBA:RefGenome.
 GO:0051384; P:response to glucocorticoid stimulus; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara. 
Interpro
 IPR008928; 6-hairpin_glycosidase-like.
 IPR010401; GDE_C.
 IPR013781; Glyco_hydro_catalytic_dom.
 IPR006421; Glycogen_debranch_met.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF06202; GDE_C 
SMART
  
PROSITE
  
PRINTS