CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026950
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Muscle type neuropilin 1 
Protein Synonyms/Alias
  
Gene Name
 NRP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
53HSYHPSEKCEWLIQAubiquitination[1]
106FRGKFCGKIAPPPVVubiquitination[1]
166KSPGFPEKYPNSLECubiquitination[1, 2]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 641 AA 
Protein Sequence
MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 60
PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 120
IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP 180
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 240
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 300
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 360
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 420
VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 480
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 540
EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEGTIN TDQECPCARA 600
LAKDAKKKKR WADSTHCRCV RSIHGEMWSS GKGVCSLDAN L 641 
Gene Ontology
 GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
 GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro.
 GO:0001525; P:angiogenesis; IEA:InterPro.
 GO:0007411; P:axon guidance; IEA:InterPro.
 GO:0007155; P:cell adhesion; IEA:InterPro.
 GO:0035767; P:endothelial cell chemotaxis; IEA:InterPro.
 GO:0009887; P:organ morphogenesis; IEA:InterPro.
 GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000421; Coagulation_fac_5/8-C_type_dom.
 IPR000859; CUB_dom.
 IPR008979; Galactose-bd-like.
 IPR014648; Neuropilin.
 IPR027146; NRP1. 
Pfam
 PF00431; CUB
 PF00754; F5_F8_type_C 
SMART
 SM00042; CUB
 SM00231; FA58C 
PROSITE
 PS01180; CUB
 PS01285; FA58C_1
 PS01286; FA58C_2
 PS50022; FA58C_3 
PRINTS