CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009617
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S3 
Protein Synonyms/Alias
  
Gene Name
 Rps3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
75ELTAVVQKRFGFPEGacetylation[1]
90SVELYAEKVATRGLCacetylation[1]
214HVSIVEPKDEILPTTubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
 DOMAIN 21 92 KH type-2.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 62 62 N6-acetyllysine (By similarity).
 MOD_RES 221 221 Phosphothreonine (By similarity).
 MOD_RES 224 224 Phosphoserine (By similarity).
 MOD_RES 242 242 Phosphothreonine (By similarity).
 CROSSLNK 90 90 Glycyl lysine isopeptide (Lys-Gly)
 CROSSLNK 202 202 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Isopeptide bond; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 243 AA 
Protein Sequence
MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG 60
EKGRRIRELT AVVQKRFGFP EGSVELYAEK VATRGLCAIA QAESLRYKLL GGLAVRRACY 120
GVLRFIMESG AKGCEVVVSG KLRGQRAKSM KFVDGLMIHS GDPVNYYVDT AVRHVLLRQG 180
VLGIKVKIML PWDPSGKIGP KKPLPDHVSI VEPKDEILPT TPISEQKGGK PEPPAMPQPV 240
PTA 243 
Gene Ontology
 GO:0022627; C:cytosolic small ribosomal subunit; IDA:RGD.
 GO:0030425; C:dendrite; IDA:RGD.
 GO:0012505; C:endomembrane system; IDA:RGD.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IC:RGD.
 GO:0006412; P:translation; IC:RGD. 
Interpro
 IPR004087; KH_dom.
 IPR015946; KH_dom-like_a/b.
 IPR004044; KH_dom_type_2.
 IPR009019; KH_prok-type.
 IPR001351; Ribosomal_S3_C.
 IPR018280; Ribosomal_S3_CS.
 IPR005703; Ribosomal_S3_euk/arc. 
Pfam
 PF07650; KH_2
 PF00189; Ribosomal_S3_C 
SMART
 SM00322; KH 
PROSITE
 PS50823; KH_TYPE_2
 PS00548; RIBOSOMAL_S3 
PRINTS