CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001820
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive 
Protein Synonyms/Alias
 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase 
Gene Name
 aroH 
Gene Synonyms/Alias
 b1704; JW1694 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
44DSRRRIEKILNGEDKacetylation[1]
51KILNGEDKRLLVIIGacetylation[1]
96VMRTYFEKPRTVVGWacetylation[1]
104PRTVVGWKGLISDPDacetylation[1]
213HMFLSPDKNGQMTIYacetylation[1]
339DTERLVEKLASAVDTacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP). 
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 348 AA 
Protein Sequence
MNRTDELRTA RIESLVTPAE LALRYPVTPG VATHVTDSRR RIEKILNGED KRLLVIIGPC 60
SIHDLTAAME YATRLQSLRN QYQSRLEIVM RTYFEKPRTV VGWKGLISDP DLNGSYRVNH 120
GLELARKLLL QVNELGVPTA TEFLDMVTGQ FIADLISWGA IGARTTESQI HREMASALSC 180
PVGFKNGTDG NTRIAVDAIR AARASHMFLS PDKNGQMTIY QTSGNPYGHI IMRGGKKPNY 240
HADDIAAACD TLHEFDLPEH LVVDFSHGNC QKQHRRQLEV CEDICQQIRN GSTAIAGIMA 300
ESFLREGTQK IVGSQPLTYG QSITDPCLGW EDTERLVEKL ASAVDTRF 348 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:EcoliWiki.
 GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IDA:EcoliWiki.
 GO:0009073; P:aromatic amino acid family biosynthetic process; IDA:EcoliWiki.
 GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR006218; DAHP1/KDSA.
 IPR006219; DHAP_synth_1. 
Pfam
 PF00793; DAHP_synth_1 
SMART
  
PROSITE
  
PRINTS