CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005089
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SAN1 
Protein Synonyms/Alias
  
Gene Name
 SAN1 
Gene Synonyms/Alias
 YDR143C; YD2943.02C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
197EEESEGTKKRKDNEGubiquitination[1]
282SCPLCRQKISESVGVubiquitination[2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Plays a specific role in mating-type regulation of yeast, by acting post-translationally to control the stability or activity of the SIR4 proteins. 
Sequence Annotation
 ZN_FING 240 280 RING-type.  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 610 AA 
Protein Sequence
MSESGQEQNR GTNTSPNNAE NNNNSNAASG PLNGGAEQTR NITVSIQYSY FTPERLAHLS 60
NISNNDNNEN NSAASGSTIA NGTGPSFGIG NGGHQPDGAL VLSFRDVPAS TPQDRLNSFI 120
SVAAQLAMER FNRLLNRPKG ISKDEFDKLP VLQVSDLPKA EGPLCSICYD EYEDEVDSTK 180
AKRKRDSENE EESEGTKKRK DNEGAPLRTT ADNDSNPSIT NATVVEPPSI PLTEQQRTLN 240
DEETNPSYKH SPIKLPCGHI FGRECIYKWS RLENSCPLCR QKISESVGVQ RAAQQDTDEV 300
AANEAAFERI RRVLYDPTAV NSTNENSSAP SENTSNTTVP TIGNASSGEQ MLSRTGFFLV 360
PQNGQPLHNP VRLPPNDSDR NGVNGPSSTT QNPPSNSGGS NNNQSPRWVP IPLTLFQFHS 420
PNPNPSASDS SASPSAANGP NSNNTSSDAT DPHHNRLRAV LDHIFNVAQR GTSDTSATTA 480
PGAQTVHNQG RNDSSSSDTT QGSSFLENIS RLTGHFTNGS RDNNNDNNHS NDQQRGGSTG 540
ENNRNNLFSS GVASYRNQNG DVTTVELRNN NSAAFPPTDE NPSQGQGSSS SDTTIHNDVP 600
NDNNEQRSSQ 610 
Gene Ontology
 GO:0005737; C:cytoplasm; IMP:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0071630; P:nucleus-associated proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.
 GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF13639; zf-RING_2 
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS