CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000857
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptogyrin-1 
Protein Synonyms/Alias
  
Gene Name
 Syngr1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
10GGAYGAGKAGGAFDPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Involved in the regulation of short-term and long-term synaptic plasticity. 
Sequence Annotation
 DOMAIN 20 173 MARVEL.
 MOD_RES 1 1 N-acetylmethionine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Cell junction; Complete proteome; Direct protein sequencing; Membrane; Reference proteome; Synapse; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 234 AA 
Protein Sequence
MEGGAYGAGK AGGAFDPYTL VRQPHTILRV VSWVFSIVVF GSIVNEGYLN NPEEEEEFCI 60
YNRNPNACSY GVTVGVLAFL TCLLYLALDV YFPQISSVKD RKKAVLSDIG VSAFWAFFWF 120
VGFCFLANQW QVSKPKDNPL NEGTDAARAA IAFSFFSIFT WAGQAVLAFQ RYQIGADSAL 180
FSQDYMDPSQ DSSMPYAPYV EPSAGSDPAG MGGTYQHPAN AFDAEPQGYQ SQGY 234 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0008021; C:synaptic vesicle; ISO:MGI.
 GO:0030672; C:synaptic vesicle membrane; IEA:Compara.
 GO:0006605; P:protein targeting; ISO:MGI.
 GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:UniProtKB.
 GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:UniProtKB. 
Interpro
 IPR008253; Marvel.
 IPR021128; MARVEL-like_dom.
 IPR016579; Synaptogyrin. 
Pfam
 PF01284; MARVEL 
SMART
  
PROSITE
 PS51225; MARVEL 
PRINTS