Tag | Content |
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CPLM ID | CPLM-022623 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inositol oxygenase |
Protein Synonyms/Alias | Aldehyde reductase-like 6; Kidney-specific protein 32; Myo-inositol oxygenase; MI oxygenase; Renal-specific oxidoreductase |
Gene Name | Miox |
Gene Synonyms/Alias | Aldrl6; Ksp32; Rsor |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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2 | ******MKVDLGPDP | acetylation | [1] | 23 | DVDPEMAKSKGSFRN | acetylation | [1] | 69 | QFGSFSYKKMTVMEA | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | |
Sequence Annotation | REGION 85 87 Substrate binding (By similarity). REGION 141 142 Substrate binding (By similarity). REGION 220 221 Substrate binding (By similarity). METAL 98 98 Iron 1 (By similarity). METAL 123 123 Iron 1 (By similarity). METAL 124 124 Iron 1 (By similarity). METAL 124 124 Iron 2 (By similarity). METAL 194 194 Iron 2 (By similarity). METAL 220 220 Iron 2 (By similarity). METAL 253 253 Iron 1 (By similarity). BINDING 29 29 Substrate (By similarity). BINDING 127 127 Substrate (By similarity). |
Keyword | Complete proteome; Cytoplasm; Iron; Metal-binding; Oxidoreductase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 285 AA |
Protein Sequence | MKVDLGPDPS LVYRPDVDPE MAKSKGSFRN YTSGPLLDRV FTTYKLMHTH QTVDFVMRKR 60 IQFGSFSYKK MTVMEAVDML DDLVDESDPD VDFPNSFHAF QTAEGIRKAH PDKDWFHLVG 120 LLHDLGKILA LWGEPQWAVV GDTFPVGCRP QASVVFCDST FQDNPDLQDP RYSTELGMYQ 180 PHCGLENVLM SWGHDEYLYQ MMKFNKFSLP SEAFYMVRFH SFYPWHTGGD YRQLCSQQDL 240 DMLPWVQEFN KFDLYTKCPD LPEVKSLRPY YQGLIDKYCP GILSW 285 |
Gene Ontology | GO:0005737; C:cytoplasm; ISS:UniProtKB. GO:0016234; C:inclusion body; ISS:UniProtKB. GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:UniProtKB. GO:0008199; F:ferric iron binding; ISS:UniProtKB. GO:0050113; F:inositol oxygenase activity; ISS:UniProtKB. GO:0050661; F:NADP binding; IDA:RGD. GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:Compara. GO:0019310; P:inositol catabolic process; ISS:UniProtKB. |
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PRINTS | |