UniProt Accession

 B7Z1T4_HUMAN; B7Z1T4 

Genbank Protein ID

 AC022966; AC099804; AK293894; AK316277 

Genbank Nucleotide ID

 BAH11620.1; BAH14648.1 

Protein Name

 Cytohesin-1 

Protein Synonyms/Alias

 cDNA FLJ54415, highly similar to Cytohesin-1; cDNA, FLJ79176, highly similar to Cytohesin-1 

Gene Name

 CYTH1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
12	KQVAMGRKKFNMDPK	ubiquitination	[1]
101	RLPGEAQKIDRMMEA	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 339 AA 

Protein Sequence

Gene Ontology

 GO:0005923; C:tight junction; IEA:Compara.
 GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0090162; P:establishment of epithelial cell polarity; IEA:Compara.
 GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro. 

Interpro

 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000904; Sec7.
 IPR023394; SEC7_alpha_orthog. 

Pfam

 PF00169; PH
 PF01369; Sec7 

SMART

 SM00233; PH
 SM00222; Sec7 

PROSITE

 PS50003; PH_DOMAIN
 PS50190; SEC7 

PRINTS