CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045132
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein AATF 
Protein Synonyms/Alias
  
Gene Name
 AATF 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
18KTKLASGKLGKGFGAacetylation[1]
21LASGKLGKGFGAFERubiquitination[1, 2, 3, 4]
41IDHILMDKERLLRRTubiquitination[2, 4, 5]
60SVYRVLGKPEPAAQPubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 154 AA 
Protein Sequence
RNRTLQKWHD KTKLASGKLG KGFGAFERSI LTQIDHILMD KERLLRRTQT KRSVYRVLGK 60
PEPAAQPVPE SLPGEPEILP QAPANAHLKD LDEEIFDDDD FYHQLLRELI ERKTSSLDPN 120
DQVAMGRQWL AIQKLRSKIH KKVDRKASKG RKLR 154 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0007155; P:cell adhesion; IEA:Compara.
 GO:0040016; P:embryonic cleavage; IEA:Compara.
 GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; IEA:Compara.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0007346; P:regulation of mitotic cell cycle; IEA:Compara.
 GO:0042254; P:ribosome biogenesis; IEA:Compara. 
Interpro
 IPR012617; AATF_C. 
Pfam
 PF08164; TRAUB 
SMART
  
PROSITE
  
PRINTS