CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030971
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ54365, highly similar to DNA replication licensing factor MCM4 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
176NVNCEHIKSFDKNLYubiquitination[1]
180EHIKSFDKNLYRQLIubiquitination[1]
399LDEEAEQKLFSEKRVubiquitination[1]
410EKRVELLKELSRKPDubiquitination[1]
496RGQYTSGKGSSAVGLubiquitination[1]
587IESQWNPKKTTIENIubiquitination[1]
712AKVRLSNKVEAIDVEubiquitination[1]
774KLILSKGKTPALKYQubiquitination[1]
779KGKTPALKYQQLFEDubiquitination[1]
818DFLTVTGKTVRLL**ubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; DNA replication; DNA-binding; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 823 AA 
Protein Sequence
MPGHLPLRDV EARIPPPRGS CSRCQPRLEW TCRALLRRTC CFPALPKCIL QLSLLTLMLE 60
GTPRSGVRGT PVRQRPDLGS AQKGLQVDLQ SDGAAAEDIV ASEQSLGQKL VIWGTDVNVA 120
ACKENFQRFL QRFIDPLAKE EENVGIDITE PLYMQRLGEI NVIGEPFLNV NCEHIKSFDK 180
NLYRQLISYP QEVIPTFDMA VNEIFFDRYP DSILEHQIQV RPFNALKTKN MRNLNPEDID 240
QLITISGMVI RTSQLIPEMQ EAFFQCQVCA HTTRVEMDRG RIAEPSVCGR CHTTHSMALI 300
HNRSLFSDKQ MIKLQESPED MPAGQTPHTV ILFAHNDLVD KVQPGDRVNV TGIYRAVPIR 360
VNPRVSNVKS VYKTHIDVIH YRKTDAKRLH GLDEEAEQKL FSEKRVELLK ELSRKPDIYE 420
RLASALAPSI YEHEDIKKGI LLQLFGGTRK DFSHTGGGKF RAEINILLCG DPGTSKSQLL 480
QYVYNLVPRG QYTSGKGSSA VGLTAYVMKD PETRQLVLQT GALVLSDNGI CCIDEFDKMN 540
ESTRSVLHEV MEQQTLSIAK AGIICQLNAR TSVLAAANPI ESQWNPKKTT IENIQLPHTL 600
LSRFDLIFLM LDPQDEAYDR RLAHHLVALY YQSEEQAEEE LLDMAVLKDY IAYAHSTIMP 660
RLSEEASQAL IEAYVDMRKI GSSRGMVSAY PRQLESLIRL AEAHAKVRLS NKVEAIDVEE 720
AKRLHREALK QSATDPRTGI VDISILTTGM SATSRKRKEE LAEALKKLIL SKGKTPALKY 780
QQLFEDIRGQ SDIAITKDMF EEALRALADD DFLTVTGKTV RLL 823 
Gene Ontology
 GO:0042555; C:MCM complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003678; F:DNA helicase activity; IEA:InterPro.
 GO:0032508; P:DNA duplex unwinding; IEA:GOC.
 GO:0006270; P:DNA replication initiation; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR008047; MCM_4.
 IPR018525; MCM_CS.
 IPR001208; MCM_DNA-dep_ATPase.
 IPR012340; NA-bd_OB-fold.
 IPR027417; P-loop_NTPase.
 IPR004039; Rubredoxin-type_fold. 
Pfam
 PF00493; MCM 
SMART
 SM00382; AAA
 SM00350; MCM 
PROSITE
 PS00847; MCM_1
 PS50051; MCM_2 
PRINTS
 PR01657; MCMFAMILY.
 PR01660; MCMPROTEIN4.