UniProt Accession

 CSK2B_YEAST; P43639; D6VUB8; Q9URG5 

Genbank Protein ID

 U21283; Z72541; BK006941 

Genbank Nucleotide ID

 AAA86829.1; CAA96719.1; DAA08079.1 

Protein Name

 Casein kinase II subunit beta 

Protein Synonyms/Alias

 CK II beta 

Gene Name

 CKB1 

Gene Synonyms/Alias

 YGL019W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
110	DEGKRRNKSPVVNKS	ubiquitination	[1]
116	NKSPVVNKSIIEHAA	ubiquitination	[1]
138	HARFILTKPGLQAMA	acetylation	[2]
138	HARFILTKPGLQAMA	ubiquitination	[3]

Reference

 [1] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.
 MOD_RES 2 2 Phosphoserine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 278 AA 

Protein Sequence

Gene Ontology

 GO:0005956; C:protein kinase CK2 complex; IDA:SGD.
 GO:0034456; C:UTP-C complex; IDA:SGD.
 GO:0030291; F:protein serine/threonine kinase inhibitor activity; IDA:SGD.
 GO:0006468; P:protein phosphorylation; IDA:SGD.
 GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:SGD.
 GO:0006359; P:regulation of transcription from RNA polymerase III promoter; IDA:SGD.
 GO:0006974; P:response to DNA damage stimulus; IDA:SGD. 

Interpro

 IPR016149; Casein_kin_II_reg-sub_a-hlx.
 IPR016150; Casein_kin_II_reg-sub_b-sht.
 IPR000704; Casein_kinase_II_reg-sub. 

Pfam

 PF01214; CK_II_beta 

SMART

 SM01085; CK_II_beta 

PROSITE

 PS01101; CK2_BETA 

PRINTS

 PR00472; CASNKINASEII.