UniProt Accession

 RPP29_HUMAN; O95707; Q5XKL7; Q6FHW9; Q9UQQ3 

Genbank Protein ID

 AF001176; Y18863; CR536569; AK314790; BC004438; BC006098 

Genbank Nucleotide ID

 AAD00893.2; CAB39167.1; CAG38806.1; BAG37321.1; AAH04438.1; AAH06098.1 

Protein Name

 Ribonuclease P protein subunit p29 

Protein Synonyms/Alias

 hPOP4 

Gene Name

 POP4 

Gene Synonyms/Alias

 RPP29 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
12	IYHALSQKEANDSDV	ubiquitination	[1]
90	ELRLFDIKPEQQRYS	ubiquitination	[1, 2]
118	RDLCSGLKPDTQPQM	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P. 

Sequence Annotation

 MOD_RES 10 10 Phosphoserine.  

Keyword

 Complete proteome; Direct protein sequencing; Hydrolase; Nucleus; Phosphoprotein; Reference proteome; tRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 220 AA 

Protein Sequence

Gene Ontology

 GO:0005655; C:nucleolar ribonuclease P complex; IEA:InterPro.
 GO:0000172; C:ribonuclease MRP complex; TAS:ProtInc.
 GO:0004526; F:ribonuclease P activity; TAS:ProtInc.
 GO:0003723; F:RNA binding; TAS:ProtInc.
 GO:0006379; P:mRNA cleavage; IEA:InterPro.
 GO:0006364; P:rRNA processing; TAS:ProtInc.
 GO:0008033; P:tRNA processing; TAS:ProtInc. 

Interpro

 IPR002730; RNase_P/MRP_p29.
 IPR016848; RNase_P/MRP_p29-subunit.
 IPR023534; Rof/RNase_P-like. 

Pfam

 PF01868; UPF0086 

SMART

 SM00538; POP4 

PROSITE

  

PRINTS