CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033164
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 DNA mismatch repair protein Msh6 
Protein Synonyms/Alias
  
Gene Name
 MSH6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
70GGHFYSAKPEILRAMubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 151 AA 
Protein Sequence
MEGYPWWPCL VYNHPFDGTF IREKGKSVRV HVQFFDDSPT RGWVSKRLLK PYTGSKSKEA 60
QKGGHFYSAK PEILRAMQRA DEALNKDKIK RLELAVCDEP SEPEEEEEME VGTTYVTDKS 120
EEDNEIESEE EVQPKTQGSR RSSRQIKKRR V 151 
Gene Ontology
 GO:0032301; C:MutSalpha complex; IEA:Compara.
 GO:0000790; C:nuclear chromatin; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0003684; F:damaged DNA binding; IEA:Compara.
 GO:0032137; F:guanine/thymine mispair binding; IEA:Compara.
 GO:0008340; P:determination of adult lifespan; IEA:Compara.
 GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Compara.
 GO:0045190; P:isotype switching; IEA:Compara.
 GO:0006298; P:mismatch repair; IEA:Compara.
 GO:0045910; P:negative regulation of DNA recombination; IEA:Compara.
 GO:0009411; P:response to UV; IEA:Compara.
 GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Compara. 
Interpro
 IPR000313; PWWP. 
Pfam
 PF00855; PWWP 
SMART
  
PROSITE
 PS50812; PWWP 
PRINTS