| Tag | Content |
|---|
| CPLM ID | CPLM-013226 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Acyl-coenzyme A dehydrogenase |
Protein Synonyms/Alias | ACDH |
Gene Name | fadE |
Gene Synonyms/Alias | yafH; b0221; JW5020 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 110 | FQGKPDWKKLHNYPQ | acetylation | [1] | | 343 | QNGPTRGKDVFVPID | acetylation | [1] | | 409 | QFKISIGKMEGIEEP | acetylation | [1] | | 537 | NDVNAFDKLLFKHIG | acetylation | [1] | | 541 | AFDKLLFKHIGHVGS | acetylation | [1] | | 689 | HYLAPSDKLDHKVAK | acetylation | [1] | | 693 | PSDKLDHKVAKILQV | acetylation | [1] | | 696 | KLDHKVAKILQVPNA | acetylation | [1] | | 748 | RICKELGKNLPFTRL | acetylation | [1] | | 765 | LAHNALVKGLIDKDE | acetylation | [1] | | 770 | LVKGLIDKDEAAILV | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the dehydrogenation of acyl-CoA. |
Sequence Annotation | |
Keyword | Complete proteome; FAD; Fatty acid metabolism; Flavoprotein; Lipid metabolism; Oxidoreductase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 814 AA |
Protein Sequence | MMILSILATV VLLGALFYHR VSLFISSLIL LAWTAALGVA GLWSAWVLVP LAIILVPFNF 60
APMRKSMISA PVFRGFRKVM PPMSRTEKEA IDAGTTWWEG DLFQGKPDWK KLHNYPQPRL 120
TAEEQAFLDG PVEEACRMAN DFQITHELAD LPPELWAYLK EHRFFAMIIK KEYGGLEFSA 180
YAQSRVLQKL SGVSGILAIT VGVPNSLGPG ELLQHYGTDE QKDHYLPRLA RGQEIPCFAL 240
TSPEAGSDAG AIPDTGIVCM GEWQGQQVLG MRLTWNKRYI TLAPIATVLG LAFKLSDPEK 300
LLGGAEDLGI TCALIPTTTP GVEIGRRHFP LNVPFQNGPT RGKDVFVPID YIIGGPKMAG 360
QGWRMLVECL SVGRGITLPS NSTGGVKSVA LATGAYAHIR RQFKISIGKM EGIEEPLARI 420
AGNAYVMDAA ASLITYGIML GEKPAVLSAI VKYHCTHRGQ QSIIDAMDIT GGKGIMLGQS 480
NFLARAYQGA PIAITVEGAN ILTRSMMIFG QGAIRCHPYV LEEMEAAKNN DVNAFDKLLF 540
KHIGHVGSNK VRSFWLGLTR GLTSSTPTGD ATKRYYQHLN RLSANLALLS DVSMAVLGGS 600
LKRRERISAR LGDILSQLYL ASAVLKRYDD EGRNEADLPL VHWGVQDALY QAEQAMDDLL 660
QNFPNRVVAG LLNVVIFPTG RHYLAPSDKL DHKVAKILQV PNATRSRIGR GQYLTPSEHN 720
PVGLLEEALV DVIAADPIHQ RICKELGKNL PFTRLDELAH NALVKGLIDK DEAAILVKAE 780
ESRLRSINVD DFDPEELATK PVKLPEKVRK VEAA 814 |
Gene Ontology | GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro. GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |