CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034627
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Potassium voltage-gated channel subfamily KQT member 2 
Protein Synonyms/Alias
  
Gene Name
 Kcnq2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
49IAGSEAPKRGSVLSKubiquitination[1]
66TGGAGAGKPPKRNAFubiquitination[1]
625ITDKDRTKGPAETELubiquitination[1]
654KQVLSMEKKLDFLVSubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Potassium; Potassium channel; Potassium transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 888 AA 
Protein Sequence
MVQKSRNGGV YPGTSGEKKL KVGFVGLDPG APDSTRDGAL LIAGSEAPKR GSVLSKPRTG 60
GAGAGKPPKR NAFYRKLQNF LYNVLERPRG WAFIYHAYVF LLVFSCLVLS VFSTIKEYEK 120
SSEGALYILE IVTIVVFGVE YFVRIWAAGC CCRYRGWRGR LKFARKPFCV IDIMVLIASI 180
AVLAAGSQGN VFATSALRSL RFLQILRMIR MDRRGGTWKL LGSVVYAHSK ELVTAWYIGF 240
LCLILASFLV YLAEKGENDH FDTYADALWW GLITLTTIGY GDKYPQTWNG RLLAATFTLI 300
GVSFFALPAG ILGSGFALKV QEQHRQKHFE KRRNPAAGLI QSAWRFYATN LSRTDLHSTW 360
QYYERTVTVP MYSSQTQTYG ASRLIPPLNQ LELLRNLKSK SGLTFRKEPQ PEPSPSQKVS 420
LKDRVFSSPR GVAAKGKGSP QAQTVRRSPS ADQSLDDSPS KVPKSWSFGD RSRARQAFRI 480
KGAASRQNSE EASLPGEDIV EDNKSCNCEF VTEDLTPGLK VSIRAVCVMR FLVSKRKFKE 540
SLRPYDVMDV IEQYSAGHLD MLSRIKSLQS RIDMIVGPPP PSTPRHKKYP TKGPTAPSRE 600
SPQYSPRVDQ IVGRGPTITD KDRTKGPAET ELPEDPSMMG RLGKVEKQVL SMEKKLDFLV 660
SIYTQRMGIP PAETEAYFGA KEPEPAPPYH SPEDSRDHAD KHGCIIKIVR STSSTGQRNY 720
AAPPVMPPAQ CPPSTSWQQS HQRHGTSPVG DHGSLVRIPP PPAHERSLSA YSGGNRASTE 780
FLRLEGTPAC RPSEAALRDS DTSISIPSVD HEELERSFSG FSISQSKENL DALASCYAAV 840
APCAKVRPYI AEGESDTDSD LCTPCGPPPR SATGEGPFGD VAWAGPRK 888 
Gene Ontology
 GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
 GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
 GO:0019226; P:transmission of nerve impulse; IEA:Compara. 
Interpro
 IPR020969; Ankyrin-G_BS.
 IPR005821; Ion_trans_dom.
 IPR003091; K_chnl.
 IPR003937; K_chnl_volt-dep_KCNQ.
 IPR003947; K_chnl_volt-dep_KCNQ2.
 IPR013821; K_chnl_volt-dep_KCNQ_C. 
Pfam
 PF00520; Ion_trans
 PF03520; KCNQ_channel
 PF11956; KCNQC3-Ank-G_bd 
SMART
  
PROSITE
  
PRINTS
 PR00169; KCHANNEL.
 PR01461; KCNQ2CHANNEL.
 PR01459; KCNQCHANNEL.