| Tag | Content |
|---|
| CPLM ID | CPLM-024649 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rho GTPase-activating protein 42 |
Protein Synonyms/Alias | Rho-type GTPase-activating protein 42 |
Gene Name | Arhgap42 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 424 | KTITSGLKNYLRCLA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act as a GTPase activator (By similarity). |
Sequence Annotation | DOMAIN 7 228 BAR.
DOMAIN 231 340 PH.
DOMAIN 342 538 Rho-GAP.
DOMAIN 783 841 SH3.
MOD_RES 778 778 Phosphoserine (By similarity).
MOD_RES 837 837 Phosphotyrosine (By similarity). |
Keyword | Coiled coil; Complete proteome; GTPase activation; Phosphoprotein; Reference proteome; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 841 AA |
Protein Sequence | MGLPTLEFSD SYLDSPDFRE RLQCHEIELE RTNKFIKELL KDGSLLIGAL RNLSMAVQKF 60
SQSLQDFQFE CIGDAETDDE ISIAQSLKEF ARLLIAVEEE RRRLIQNAND VLIAPLEKFR 120
KEQIGAAKAD SQIGREHQNF YEASLEYVFK IQEVQEKKKF EFVEPLLSFL QGLFTFYHEG 180
YELAQEFAPY KQQLQFNLQN TRNNFESTRQ EVERLMQRMK SANQDYRPPS QWTMEGYLYV 240
QEKRPLGFTW TKHYCTYDKG SKMFTMSVSD VKASGKMNGL VTGSPEMFKL KSCIRRKTDS 300
IDKRFCFDIE VVERHGIITL QAFSEANRKL WLEAMDGKEP IYTLPAIISK KEEMYLNEAG 360
FNFVRKCIQA VEMRGITILG LYRIGGVNSK VQKLMNTTFS PKSPPDMDID IELWDNKTIT 420
SGLKNYLRCL AEPLMTYKLH KDFIIAVKSD DQNYRVEAVH ALVHKLPEKN REMLDILIKH 480
LLKVSLHSQQ NLMTISNLGV IFGPTLMRAQ EETVAAMMNI KFQNIVVEIL IEHYEKIFHT 540
APDPNIPLPQ PQSRSGSRRT RAICLSTGSR KPRGRYTPCL AEPDSDSYSS SPDSTPMGSI 600
ESLSSHSSEQ NSTTKSTACQ PREKSGGIPW ITTPSSSNGQ KSQGLWTTSP ESSSREDATK 660
TDVESDCQSV ASITIPGNVS PPIDLVKKGP YGLSGLKRSS ASSSLRSISA AEGNKSYSGS 720
IQSLTSIGSK ESPKAIPNPE LPPKMCRRLR LDTASSNGYQ RPGSVVAAKA QLFENAGSPK 780
PVSSGRQAQA MYSCKAEHSH ELSFPQGAIF SNVHPSVEPG WLKATYEGRT GLVPENYVVF 840
L 841 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0043547; P:positive regulation of GTPase activity; IEA:GOC. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |